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  1. Article

    Open Access

    Recurrent cerebrovascular events after recent small subcortical infarction

    Recent small subcortical infarcts (RSSI) are the neuroimaging hallmark feature of small vessel disease (SVD)-related acute lacunar stroke. Long-term data on recurrent cerebrovascular events including their aet...

    Melanie Haidegger, Nina Klock, Markus Kneihsl, Simon Fandler-Höfler in Journal of Neurology (2024)

  2. No Access

    Article

    Neurofilaments as biomarkers in neurological disorders — towards clinical application

    Neurofilament proteins have been validated as specific body fluid biomarkers of neuro-axonal injury. The advent of highly sensitive analytical platforms that enable reliable quantification of neurofilaments in...

    Michael Khalil, Charlotte E. Teunissen, Sylvain Lehmann in Nature Reviews Neurology (2024)

  3. Article

    Open Access

    Cerebral white matter hyperintensities indicate severity and progression of coronary artery calcification

    Cerebral white matter hyperintensities (WMH) have been associated with subclinical atherosclerosis including coronary artery calcification (CAC). However, previous studies on this association are limited by on...

    Markus Kneihsl, Thomas Gattringer, Edith Hofer, Peter P. Rainer in Scientific Reports (2024)

  4. Article

    Open Access

    Frequency and predictors of poststroke epilepsy after mechanical thrombectomy for large vessel occlusion stroke: results from a multicenter cohort study

    Poststroke epilepsy (PSE) represents an important complication of stroke. Data regarding the frequency and predictors of PSE in patients with large-vessel occlusion stroke receiving mechanical thrombectomy (MT...

    Joachim Gruber, Thomas Gattringer, Georg Mayr in Journal of Neurology (2023)

  5. Article

    Open Access

    Large diameter hemicraniectomy does not improve long-term outcome in malignant infarction

    In malignant cerebral infarction decompressive hemicraniectomy has demonstrated beneficial effects, but the optimum size of hemicraniectomy is still a matter of debate. Some surgeons prefer a large-sized hemic...

    Dominik Lehrieder, Hans-Peter Müller, Jan Kassubek, Nils Hecht in Journal of Neurology (2023)

  6. Article

    Open Access

    Long-term outcome after decompressive hemicraniectomy for malignant middle cerebral artery infarction

    Although decompressive hemicraniectomy (DHC) is a lifesaving treatment strategy for patients with malignant middle cerebral artery infarction (mMCAi), only one in four patients achieves low to moderate post-st...

    Natalie Berger, Anna Brunner, Gerit Wünsch, Oliver Nistl in Journal of Neurology (2023)

  7. No Access

    Chapter

    Hemodynamic Changes on Transcranial Duplex Sonography to Predict Poor Outcome after Mechanical Thrombectomy

    Endovascular stroke treatment with mechanical thrombectomy (MT) has become the standard therapy for intracranial large vessel occlusion (LVO). The most serious MT-related complication is secondary intracranial...

    Markus Kneihsl, Kurt Niederkorn, Hannes Deutschmann in Mind, Brain and Education (2023)

  8. Article

    Open Access

    Serum glial fibrillary acidic protein is sensitive to acute but not chronic tissue damage in cerebral small vessel disease

    Serum glial fibrillary acidic protein (sGFAP) has been proposed as a biomarker in various neurological diseases but has not yet been systematically investigated in patients with cerebral small vessel disease (...

    Thomas Gattringer, Christian Enzinger, Daniela Pinter in Journal of Neurology (2023)

  9. No Access

    Article

    Time trends in stroke severity in the years 2005 to 2020: results from the Austrian Stroke Unit Registry

    With aging population, there is an increase of atrial fibrillation (AF) and other vascular risk factors. We investigated trends in stroke severity at hospital admission with respect to AF and other risk factor...

    Alexandra Bernegger, Dominika Mikšová, Alexandra Posekany in Journal of Neurology (2022)

  10. Article

    Open Access

    Thyroid dysfunction in cerebral venous thrombosis: a retrospective cohort study

    Cerebral venous thrombosis (CVT) is a multifactorial disease with a variety of related conditions and risk factors. Thyroid dysfunction—especially hyperthyroidism—has been linked to CVT, but this is mainly bas...

    Simon Fandler-Höfler, Stefan Pilz, Marion Ertler, Melanie Haidegger in Journal of Neurology (2022)

  11. Article

    Magnetic resonance black-blood imaging to facilitate diagnosis of cerebral venous thrombosis?

    Simon Fandler-Höfler, Thomas Gattringer in European Radiology (2022)

  12. No Access

    Article

    Letter to the Editor Regarding “Internal Carotid Artery Pseudoaneurysm Secondary to Spontaneous Dissection: Treatment with Endovascular Stentgraft Repair” Published by Zakeri et al

    Elke R. Gizewski, Hannes Deutschmann in CardioVascular and Interventional Radiology (2022)

  13. Article

    Open Access

    Acute and Chronic Kidney Dysfunction and Outcome After Stroke Thrombectomy

    Data on the impact of kidney dysfunction on outcome in patients with stroke due to large vessel occlusion are scarce. The few available studies are limited by only considering single kidney parameters measured...

    Simon Fandler-Höfler, Balazs Odler, Markus Kneihsl in Translational Stroke Research (2021)

  14. Article

    Open Access

    Hospital admissions of acute cerebrovascular diseases during and after the first wave of the COVID-19 pandemic: a state-wide experience from Austria

    We investigated hospital admission rates for the entire spectrum of acute cerebrovascular diseases and of recanalization treatments for ischaemic stroke (IS) in the Austrian federal state of Styria during and ...

    Thomas Gattringer, Simon Fandler-Höfler, Markus Kneihsl in Journal of Neurology (2021)

  15. Article

    Open Access

    Blood biomarkers of progressive atherosclerosis and restenosis after stenting of symptomatic intracranial artery stenosis

    In-stent restenosis (ISR) represents a major complication after stenting of intracranial artery stenosis (ICAS). Biomarkers derived from routine blood sampling including C-reactive protein (CRP), neutrophil-to...

    Melanie Haidegger, Markus Kneihsl, Kurt Niederkorn in Scientific Reports (2021)

  16. Article

    Open Access

    Early Progressive Changes in White Matter Integrity Are Associated with Stroke Recovery

    Information on microstructural white matter integrity has been shown to explain post-stroke recovery beyond clinical measures and focal brain damage. Especially, knowledge about early white matter changes migh...

    Daniela Pinter, Thomas Gattringer, Simon Fandler-Höfler in Translational Stroke Research (2020)

  17. Article

    Open Access

    Relationship between stroke etiology and collateral status in anterior circulation large vessel occlusion

    Clinical outcome after mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke is influenced by the intracerebral collateral status. We tested the hypothesis that patients with preexisting ipsilat...

    Eva Hassler, Markus Kneihsl, Hannes Deutschmann, Nicole Hinteregger in Journal of Neurology (2020)

  18. Article

    Open Access

    Predictors of Lesion Cavitation After Recent Small Subcortical Stroke

    Morphologic evolution of recent small subcortical infarcts (RSSI) ranges from lesion disappearance to lacune formation and the reasons for this variability are still poorly understood. We hypothesized that dif...

    Thomas Gattringer, Maria Valdes Hernandez, Anna Heye in Translational Stroke Research (2020)

  19. Article

    Open Access

    Single mean arterial blood pressure drops during stroke thrombectomy under general anaesthesia are associated with poor outcome

    We examined the influence of periprocedural blood pressure (BP), especially critical BP drops, on 3-month functional outcome in stroke patients undergoing mechanical thrombectomy (MT) under general anaesthesia...

    Simon Fandler-Höfler, Stefan Heschl, Placido Argüelles-Delgado in Journal of Neurology (2020)

  20. Article

    Open Access

    Apps in der Sekundärprävention nach Schlaganfall

    Laut der INTERSTROKE Studie werden etwa 90 % des Risikos für einen ischämischen Schlaganfall durch beeinflussbare Risikofaktoren (z. B. Bluthochdruck, Übergewicht, Rauchen) bedingt. Durch eine Verringerung die...

    Viktoria Fruhwirth, Christian Enzinger in Wiener Medizinische Wochenschrift (2020)

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