-
Article
Open AccessCorrection to: Occurrence of mental illness following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
Following publication of the original article [1], the author reported that, because of a programming error, incorrect sentences and incorrect Table 3 has been published. The correct sentences and Table 3 are ...
-
Article
Open AccessAssessment of total, ligand-induced peroxisome proliferator activated receptor γ ligand activity in serum
Humans are exposed to a complex mixture of environmental chemicals that impact bone and metabolic health, and traditional exposure assessments struggle to capture these exposure scenarios. Peroxisome prolifera...
-
Chapter
Mixtures: Contrasting Perspectives from Toxicology and Epidemiology
Investigation of the health effects of mixtures will benefit from the cooperation of toxicologists and epidemiologists. This chapter provides insight into the commonalities and differences in the viewpoint and...
-
Article
Open AccessExploring associations between prenatal solvent exposures and teenage drug and alcohol use: a retrospective cohort study
Investigating the effects of prenatal and childhood exposures on behavioral health outcomes in adolescence is challenging given the lengthy period between the exposure and outcomes. We conducted a retrospectiv...
-
Article
Toddler’s behavior and its impacts on exposure to polybrominated diphenyl ethers
Children have higher polybrominated diphenyl ether (PBDE) body burdens than adults, which may be related to hand-to-mouth behavior. We investigate associations between children’s behavior, including hand-to-mo...
-
Article
Open AccessCharacterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling
The potential for chemical exposures to exacerbate the development and/or prevalence of metabolic disorders, such as obesity, is currently of great societal concern. Various in vitro assays are available to asses...
-
Article
Open AccessAssociations between residence at birth and mental health disorders: a spatial analysis of retrospective cohort data
Mental health disorders impact approximately one in four US adults. While their causes are likely multifactorial, prior research has linked the risk of certain mental health disorders to prenatal and early chi...
-
Article
Open AccessLong-term health effects of early life exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
While adult exposure to PCE is known to have toxic effects, there is little information on the long-term impact of prenatal and early childhood exposure. We undertook a retrospective cohort study to examine th...
-
Article
Exposure to Polybrominated Diphenyl Ethers in the Indoor Environment
Polybrominated diphenyl ethers (PBDEs) are fire retardants used in consumer products such as foam-containing furniture and electronics. This paper reviews human exposure to PBDEs in North America, applying the...
-
Article
Open AccessIndividual-level space-time analyses of emergency department data using generalized additive modeling
Although daily emergency department (ED) data is a source of information that often includes residence, its potential for space-time analyses at the individual level has not been fully explored. We propose tha...
-
Article
Open AccessSocial disparities in exposures to bisphenol A and polyfluoroalkyl chemicals: a cross-sectional study within NHANES 2003-2006
Bisphenol A (BPA) and polyfluoroalkyl chemicals (PFCs) are suspected endocrine disrupting compounds known to be ubiquitous in people's bodies. Population disparities in exposure to these chemicals have not bee...
-
Article
Open AccessOccurrence of mental illness following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
While many studies of adults with solvent exposure have shown increased risks of anxiety and depressive disorders, there is little information on the impact of prenatal and early childhood exposure on the subs...
-
Article
Open AccessAffinity for risky behaviors following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
Many studies of adults with acute and chronic solvent exposure have shown adverse effects on cognition, behavior and mood. No prior study has investigated the long-term impact of prenatal and early childhood e...
-
Article
Open AccessRisk of breast cancer following exposure to tetrachloroethylene-contaminated drinking water in Cape Cod, Massachusetts: reanalysis of a case-control study using a modified exposure assessment
Tetrachloroethylene (PCE) is an important occupational chemical used in metal degreasing and drycleaning and a prevalent drinking water contaminant. Exposure often occurs with other chemicals but it occurred a...
-
Article
Open AccessA power comparison of generalized additive models and the spatial scan statistic in a case-control setting
A common, important problem in spatial epidemiology is measuring and identifying variation in disease risk across a study region. In application of statistical methods, the problem has two parts. First, spatia...
-
Article
Open AccessA multilevel non-hierarchical study of birth weight and socioeconomic status
It is unclear whether the socioeconomic status (SES) of the community of residence has a substantial association with infant birth weight. We used multilevel models to examine associations of birth weight with...
-
Article
Open AccessSpatial analysis of learning and developmental disorders in upper Cape Cod, Massachusetts using generalized additive models
The spatial variability of three indicators of learning and developmental disability (LDD) was assessed for Cape Cod, Massachusetts. Maternal reports of receiving special education services, attention deficit ...
-
Article
Open AccessPrenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study
Prior animal and human studies of prenatal exposure to solvents including tetrachloroethylene (PCE) have shown increases in the risk of certain congenital anomalies among exposed offspring.
-
Article
Open AccessParticipant experiences in a breastmilk biomonitoring study: A qualitative assessment
Biomonitoring studies can provide information about individual and population-wide exposure. However they must be designed in a way that protects the rights and welfare of participants. This descriptive qualit...
-
Article
Open AccessExposure to Tetrachloroethylene-Contaminated Drinking Water and the Risk of Pregnancy Loss
There is little information on the impact of solvent-contaminated drinking water on pregnancy outcomes. This retrospective cohort study examined whether maternal exposure to tetrachloroethylene (PCE)-contamina...
