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Article
Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach
Available drugs have been used as an urgent attempt through clinical trials to minimize severe cases of hospitalizations with Coronavirus disease (COVID-19), however, there are limited data on common pharmacog...
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Article
Open AccessExtensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. ...
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Article
Open AccessTranscriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation
Activating mutations in KRAS frequently occur in colorectal cancer (CRC) patients, leading to resistance to EGFR-targeted therapies.
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Article
Open AccessUsing biological networks to integrate, visualize and analyze genomics data
Network biology is a rapidly develo** area of biomedical research and reflects the current view that complex phenotypes, such as disease susceptibility, are not the result of single gene mutations that act i...
