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within Theodore N. Mellin Remove this filter Animal Genetics and Genomics Remove this filter

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  1. No Access

    Article

    Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

    Genetic1,2,3,4,5,6,7,8 and pharmacological6,9,10,11,12 studies have defined a role for the melanocortin-4 receptor (Mc4r) in the regulation of energy homeostasis. The physiological function of Mc3r, a melanocorti...

    Airu S. Chen, Donald J. Marsh, Myrna E. Trumbauer, Easter G. Frazier… in Nature Genetics (2000)

  2. No Access

    Article

    Role of the melanocortin-4 receptor in metabolic rate and food intake in mice

    We evaluated the role of the melanocortin-4 receptor (MC-4R) in the control of metabolic rate and food intake in mice. Intraperitoneal administration of the non-selective MC-R agonist melanotan II (MT-II; a cy...

    Airu S. Chen, Joseph M. Metzger, Myrna E. Trumbauer, **ao-ming Guan… in Transgenic Research (2000)