6 Result(s)
within
Thais Mauad
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessQuantification of airborne SARS-CoV-2 genomic particles in different hospital settings
We quantified the presence of SARS-CoV-2 RNA in the air of different hospital settings and the autopsy room of the largest medical centre in Sao Paulo, Brazil. Real-time reverse-transcription PCR was used to d...
-
Article
Open AccessA single-centre, retrospective study of the incidence of invasive fungal infections during 85 years of autopsy service in Brazil
Autopsy continues to play an essential role in monitoring opportunistic fungal infections. However, few studies have analysed the historical trends of fungal infections in autopsies. Here, we analyse available...
-
Article
Open AccessNrf2 positively regulates autophagy antioxidant response in human bronchial epithelial cells exposed to diesel exhaust particles
Diesel exhaust particles (DEP) are known to generate reactive oxygen species in the respiratory system, triggering cells to activate antioxidant defence mechanisms, such as Keap1-Nrf2 signalling and autophagy....
-
Article
Open AccessSevere pulmonary disease in an adult primary ciliary dyskinesia population in Brazil
Primary Ciliary Dyskinesia (PCD) is underdiagnosed in Brazil. We enrolled patients from an adult service of Bronchiectasis over a two-year period in a cross-sectional study. The inclusion criteria were lateral...
-
Article
Open AccessThe Th17/Treg Cytokine Imbalance in Chronic Obstructive Pulmonary Disease Exacerbation in an Animal Model of Cigarette Smoke Exposure and Lipopolysaccharide Challenge Association
We proposed an experimental model to verify the Th17/Treg cytokine imbalance in COPD exacerbation. Forty C57BL/6 mice were exposed to room air or cigarette smoke (CS) (12 ± 1 cigarettes, twice a day, 30 min/ex...
-
Article
Open AccessA Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages
The enzyme tartrate resistant acid phosphatase (TRAP, two isoforms 5a and 5b) is highly expressed in alveolar macrophages, but its function there is unclear and potent selective inhibitors of TRAP are required...
