17 Result(s)

Chapter

Development of PVA Hydrogels with Superior Lubricity for Artificial Cartilage

Physically cross-linked poly(vinyl alcohol) (PVA) gels are versatile biomaterials with their excellent biocompatibility and mechanical strength. Since the late 1970s, the semicrystalline PVA gels prepared by a...

Atsushi Suzuki, Saori Sasaki, Teruo Murakami in Rheology of Biological Soft Matter (2017)

Article

Interaction of magnesium oxide with gastric acid secretion inhibitors in clinical pharmacotherapy

Magnesium oxide (MgO), a short-term osmotic laxative, is converted into MgCl₂ under acidic condition in the stomach and then Mg(HCO₃)₂ in the intestinal tract, where Mg(HCO₃)₂ induces the water exudation into the...

Miho Yamasaki, Sachiyo Funakoshi… in European Journal of Clinical Pharmacology (2014)

Article

Comparison of In Vivo with In Vitro Pharmacokinetics of Mercury Between Methylmercury Chloride and Methylmercury Cysteine Using Rats and Caco2 Cells

The in vivo and in vitro pharmacokinetics of mercury (Hg) were compared between methylmercury chloride (MeHg·Cl) and methylmercury cysteine (MeHg-Cys) using rats and Caco2 cells because humans can be exposed t...

Nobuhiro Mori, Megumi Yamamoto, Eri Tsukada… in Archives of Environmental Contamination an… (2012)

Chapter and Conference Paper

Wear Behaviour of an Artificial Cartilage Material for Hemiarthroplasty

Hemiarthroplasty is applied if one surface of natural cartilage has diseases but another cartilage surface is healthy. Ultra-high molecular weight polyethylene (UHMWPE), metallic and ceramic materials have bee...

Kazuhiro Nakashima, Yoshinori Sawae… in 6th World Congress of Biomechanics (WCB 20… (2010)

Article

Differential Effect of Acute Hepatic Failure on in Vivo and in Vitro P-Glycoprotein Functions in the Intestine

Purpose. The expression and function of P-glycoprotein (P-gp) in the intestine in carbon tetrachloride-induced acute hepatic failure (AHF) were evaluated in rats.

Ryoko Yumoto, Teruo Murakami, Mikihisa Takano in Pharmaceutical Research (2003)

Article

Role of P-Glycoprotein in Ocular Clearance of Rhodamine 123 in Rabbits

Tetsu Kajikawa, Hiromu K. Mishima, Teruo Murakami… in Pharmaceutical Research (2000)

Chapter and Conference Paper

Biotribological Aspects of Natural Synovial Joints and Artificial Joints

Human joints play important roles in various daily activities and their durability depends on the lubrication mechanism. In this paper, the biotribological aspects such as friction, wear and lubrication in bot...

Teruo Murakami in Human Biomechanics and Injury Prevention (2000)

Article

Quantitative analysis of three-dimensional complexity and connectivity changes in trabecular microarchitecture in relation to aging, menopause, and inflammation

There are several types of bone loss besides that associated with normal aging, eg, that associated with the menopause, and that associated with chronic inflammation, and these are considered to be caused by ...

Taro Mawatari, Hiromasa Miura, Hidehiko Higaki… in Journal of Orthopaedic Science (1999)

Article

Soft Drugs 19. Pharmacokinetics, Metabolism and Excretion of a Novel Soft Corticosteroid, Loteprednol Etabonate, in Rats

Purpose. Pharmacokinetics, metabolism and excretion of loteprednol etabonate (LE) were investigated in rats.

Nicholas Bodor, Whei-Mei Wu, Teruo Murakami, Steven Engel in Pharmaceutical Research (1995)

Article

Soft Drugs 18. Oral and Rectal Delivery of Loteprednol Etabonate, a Novel Soft Corticosteroid, in Rats—for Safer Treatment of Gastrointestinal Inflammation

Purpose. As a safe anti-inflammatory corticosteroid, the utility of loteprednol etabonate (LE) for the treatment of gastrointestinal inflammation, via oral and rectal administration, was investigated in rats.

Nicholas Bodor, Teruo Murakami, Whei-Mei Wu in Pharmaceutical Research (1995)

Article

Decanoic Acid Induced Enhancement of Rectal Absorption of Hydrophilic Compounds in Rats

The enhancing effect of decanoic acid (CIO) on the rectal absorption of phenolsulfonphtalein (PSP) was analyzed with a pharmacokinetic model. The transfer index of PSP from the rectal lumen to the epithelial l...

Koji Takahashi, Teruo Murakami, Ryoko Yumoto, Tomomi Hattori… in Pharmaceutical Research (1994)

Article

Pharmacokinetic Analysis of the Absorption Enhancing Action of Decanoic Acid and Its Derivatives in Rats

The enhancing action of decanoic acid (C1O) and its derivatives on mucosal absorption of phenolsulfonphthalein (PSP) in the jejunum or colon was analyzed using pharmacokinetics in rats. After administration of...

Koji Takahashi, Teruo Murakami, Atsuko Kamata, Ryoko Yumoto… in Pharmaceutical Research (1994)

Article

Phosphatidylserine as a Determinant for the Tissue Distribution of Weakly Basic Drugs in Rats

Interorgan variation in tissue distribution of weakly basic drugs such as quinidine, propranolol, and imipramine was investigated as a function of binding to phosphatidylserine (PhS) in tissues. Tissue distrib...

Noboru Yata, Toshihiko Toyoda, Teruo Murakami, Akio Nishiura… in Pharmaceutical Research (1990)

Article

Role of Phosphatidylserine in the Cellular and Subcellular Lung Distribution of Quinidine in Rats

The role of phosphatidylserine in the cellular and subcellular lung distribution of quinidine was investigated in rats, since quinidine was found to bind preferentially to phosphatidylserine. The concentration...

Akio Nishiura, Teruo Murakami, Yutaka Higashi, Noboru Yata in Pharmaceutical Research (1988)