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  1. Article

    Open Access

    MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing

    The metabolic switch from oxidative phosphorylation to glycolysis is required for tumorigenesis in order to provide cancer cells with energy and substrates of biosynthesis. Therefore, it is important to elucid...

    Lili Yu, **chul Kim, Lei Jiang, Bingbing Feng, Yue Ying… in Nature Communications (2020)

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  2. Article

    Open Access

    Core pluripotency factors promote glycolysis of human embryonic stem cells by activating GLUT1 enhancer

    Human embryonic stem cells (hESCs) depend on glycolysis for energy and substrates for biosynthesis. To understand the mechanisms governing the metabolism of hESCs, we investigated the transcriptional regulatio...

    Lili Yu, Kai-yuan Ji, Jian Zhang, Yanxia Xu, Yue Ying, Taoyi Mai… in Protein & Cell (2019)

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