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Article
Open AccessAssessing hypo-arousal during reward anticipation with pupillometry in patients with major depressive disorder: replication and correlations with anhedonia
Major depressive disorder (MDD) is a devastating and heterogenous disorder for which there are no approved biomarkers in clinical practice. We recently identified anticipatory hypo-arousal indexed by pupil res...
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Article
Open AccessPrediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings
Heterogeneity in the clinical presentation of major depressive disorder and response to antidepressants limits clinicians’ ability to accurately predict a specific patient’s eventual response to therapy. Valid...
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Article
Open AccessCorrection to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
Upon publication of the original article [1] it was highlighted by the authors that a transposition error affected Additional file 1, causing the misplacement of several columns and rendering the table difficu...
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Article
Open AccessLifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
Chronic psychological stress is associated with accelerated aging and increased risk for aging-related diseases, but the underlying molecular mechanisms are unclear.
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Article
The ‘Early Developmental Stages of Psychopathology (EDSP) study’: a 20-year review of methods and findings
The “Early Developmental Stages of Psychopathology (EDSP)” study is a prospective-longitudinal study program in a community sample (Munich, Germany) of adolescents and young adults. The program was launched in...
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Article
Calculating control variables with age at onset data to adjust for conditions prior to exposure
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Article
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
The stress hormone–regulating hypothalamic-pituitary-adrenal (HPA) axis has been implicated in the causality1 as well as the treatment of depression2. To investigate a possible association between genes regulatin...
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Poster
Objective: One of the most powerful medications that have very broad aspects of clinical application are the selective serotonin reuptake inhibitors (SSRI). We use SSRI as a first choice agents in tr...
