Early Nutrition Programming and Health Outcomes in Later Life
Obesity and Beyond
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Article
Open AccessInverse association between use of broad spectrum penicllin with beta-lactamase inhibitors and prevalence of type 1 diabetes mellitus in Europe
Increasing incidence of type 1 diabetes is supposed to be induced by environmental factors. Microbiome modulated by antibiotics seems to serve as one of the environmental factors which could influence the deve...
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Article
Open AccessSaturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat
We investigated the effect of dietary fats on the incorporation of saturated (SAFAs) and monounsaturated dietary fatty acids (MUFAs) into plasma phospholipids and the regulation of the expression of lipid-meta...
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Article
Contribution of n-3 long-chain polyunsaturated fatty acids to human milk is still low in Hungarian mothers
Maternal diet has decisive influence on the fatty acid composition of human milk. Fifteen years ago, we found outstandingly low contribution of docosahexaenoic acid (DHA) to human milk in a small group of Hung...
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Article
Effect of high versus low doses of fat and vitamin A dietary supplementation on fatty acid composition of phospholipids in mice
Dietary fat and vitamin A provide important precursors for potent bioactive ligands of nuclear hormone receptors, which regulate various enzymes involved in lipid homeostasis, metabolism and inflammation. We ...
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Article
Open AccessEffect of folate intake on health outcomes in pregnancy: a systematic review and meta-analysis on birth weight, placental weight and length of gestation
The beneficial effect of folic acid supplementation before and shortly after conception is well recognized, whereas the effect of supplementation during the second and third trimesters is controversial and poo...
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Article
Effect of Synthetic Ligands of PPAR α, β/δ, γ, RAR, RXR and LXR on the Fatty Acid Composition of Phospholipids in Mice
Nuclear hormone receptors are transcription factors that can be activated by nutrition-derived ligands and alter the expression of various specific target genes. Stearoyl-Coenzyme A desaturase (SCD1) converts ...
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Article
Fatty acid composition of erythrocyte membrane lipids in healthy subjects from birth to young adulthood
The fatty acid composition of erythrocyte membrane lipids may better reflect the fatty acid status of the organism than the fatty acid composition of plasma lipids. The present study aimed to provide normal va...
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Book and Conference Proceedings
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Chapter and Conference Paper
Obesity Related Programming Statements in Materials on Infant Feeding Aimed at Parents in Five European Countries
Early nutrition programming as an origin of obesity is well acknowledged, but to what extent is this concept communicated to parents? In five European countries, UK, Finland (FI), Germany (DE), Hungary (HU) an...
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Chapter and Conference Paper
Effects of Supplementing LCPUFA to the Diet of Pregnant Women: Data from RCT
Randomised controlled trials (RCTs) investigating the effect of n-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation on pregnancy outcomes were recently systematically reviewed for both low-risk ...
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Chapter and Conference Paper
Obesity Related Programming Statements in Infant Feeding Policies in Five European Countries
The aim of this study was to know how the early nutrition programming concept and its relation with long-term diseases such as obesity is reflected in policy recommendations on infant nutrition in five Europea...
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Chapter and Conference Paper
Trans Isomeric and LCPUFA Are Inversely Correlated in Erythrocyte Membrane Lipids at Mid-gestation
Fatty acid composition of erythrocyte phosphatidylcholines was determined by high-resolution capillary gas chromatography in Spanish (n = 120), German (n = 78) and Hungarian (n = 43) expectant women at the 20t...
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Chapter and Conference Paper
Infant Feeding and the Concept of Early Nutrition Programming: A Comparison of Qualitative Data from Four European Countries
The concept of early nutrition programming is appearing in policy documents, leaflets and magazine articles with different types of statements. However, the level of representation and influence of this concep...
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Article
Determination of Carnitine Ester Patterns During the Second Half of Pregnancy, at Delivery, and in Neonatal Cord Blood by Tandem Mass Spectrometry: Complex and Dynamic Involvement of Carnitine in the Intermediary Metabolism
We studied plasma concentrations of free carnitine and 30 carnitine esters by electron spray ionization (ESI) tandem mass spectrometry in 37 pregnant women at the 20th and 30th weeks of gestation and at delive...
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Article
Neurologic Condition of Healthy Term Infants at 18 Months: Positive Association With Venous Umbilical DHA Status and Negative Association With Umbilical Trans-fatty Acids
Prenatal long-chain polyunsaturated fatty acids (LCPUFAs) and trans-fatty acids may affect neurodevelopment. In healthy term children, we determined relationships between relative fatty acid contents of umbilical...
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Article
Relationship Between Umbilical Cord Essential Fatty Acid Content and the Quality of General Movements of Healthy Term Infants at 3 Months
Prenatal essential fatty acid (EFA) status might be an important factor in the development of the central nervous system (CNS). The aim of the present study was to evaluate the relationship between the fatty a...
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Chapter and Conference Paper
Trans isomeric fatty acids as confounding variables in studies on perinatal LC-PUFA supply
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Chapter and Conference Paper
Effect of N-3 Polyunsaturated Fatty Acid Supplementation in Pregnancy: The Nuheal Trial
In this placebo controlled, randomised, double blind trial, pregnant women received from the 20th week of gestation onwards either 500 mg docosahexaenoic acid (DHA), 400 mg 5-methyl-tetra-hydro-folate (5-MTHF), o...
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Article
Trans isomeric octadecenoic acids are related inversely to arachidonic acid and DHA and positively related to mead acid in umbilical vessel wall lipids
Long-chain PUFA play an important role in early human neurodevelopment. Significant inverse correlations were reported between values of trans isomeric and long-chain PUFA in plasma lipids of preterm infants and ...
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Article
Systematic review of fatty acid composition of plasma phospholipids of venous cord blood in full-term infants
The purpose of this review was to systematically evaluate the variability of the fatty acid composition of venous cord blood phospholipids in different populations. In an attempt to review published evidence ...
