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  1. Article

    Open Access

    Survey on patients with undiagnosed diseases in Japan: potential patient numbers benefiting from Japan’s initiative on rare and undiagnosed diseases (IRUD)

    There is now an international partnership to establish global programs for patients with rare and undiagnosed diseases, involving interdisciplinary expert panels and phenotype-driven genetic analyses utilizing...

    Takeya Adachi, Noriaki Imanishi, Yasushi Ogawa… in Orphanet Journal of Rare Diseases (2018)

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  2. No Access

    Chapter

    Improved Diagnosis and Care for Rare Diseases through Implementation of Precision Public Health Framework

    Public health relies on technologies to produce and analyse data, as well as effectively develop and implement policies and practices. An example is the public health practice of epidemiology, which relies on ...

    Gareth Baynam, Faye Bowman, Karla Lister… in Rare Diseases Epidemiology: Update and Ove… (2017)

  3. No Access

    Article

    Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

    Hair follicle–derived cytokines control the tropism and retention of memory T cells in the skin and promote lymphoma.

    Takeya Adachi, Tetsuro Kobayashi, Eiji Sugihara, Taketo Yamada… in Nature Medicine (2015)

  4. No Access

    Article

    Development of hypertension within 2 weeks of initiation of sorafenib for advanced hepatocellular carcinoma is a predictor of efficacy

    Sorafenib is an agent that inhibits vascular endothelial growth factor and is associated with onset or worsening of hypertension in some patients. We conducted a retrospective analysis of whether the developme...

    Noriyuki Akutsu, Shigeru Sasaki… in International Journal of Clinical Oncology (2015)

  5. Article

    Open Access

    Comparison of basophil activation test and lymphocyte transformation test as diagnostic assays for drug hypersensitivity

    Takeya Adachi, Hayato Takahashi, Takeru Funakoshi… in Clinical and Translational Allergy (2014)

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  6. No Access

    Article

    Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin

    Hair is a skin component that functions as a physical barrier and thermal regulator. Nagao and colleagues show that hair follicles recruit Langerhans cells to the epidermis via the secretion of various chemoki...

    Keisuke Nagao, Tetsuro Kobayashi, Kazuyo Moro, Manabu Ohyama… in Nature Immunology (2012)

  7. No Access

    Article

    Carcinoma of duodenum arising from Brunner's gland

    Kimishige Akino, Yoshihiro Kondo, Atsumori Ueno… in Journal of Gastroenterology (2002)

  8. Article

    Assignment of the human UDP-GalNAc:polypeptide,N-acetylgalactosaminyl transferase-type-2 gene to chromosomal region 1q42 by fluorescencein situ hybridization

    Setsuo Takai, Yuji Hinoda, Takeya Adachi… in Japanese Journal of Human Genetics (1997)

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  9. No Access

    Article

    A human UPD-GalNAc: polypeptide, N-acetylgalactosaminyltranferase type 1 gene is located at the chromosomal region 18q12.1

    The cDNA clone encoding human UDP-N-acetyl-α-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase-1 (GalNAc-T1) was isolated from colon tissue by a reverse transcriptase-polymerase chain reaction (RT-PC...

    Setsuo Takai, Yuji Hinoda, Takeya Adachi, Kohzoh Imai, M. Oshima in Human Genetics (1997)