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  1. Article

    Open Access

    Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis

    Bone loss due to smoking represents a major risk factor for fractures and bone osteoporosis. Signaling through the aryl hydrocarbon receptor (AhR) and its ligands contributes to both bone homeostasis and infla...

    Yuri Yoshikawa, Takashi Izawa, Yusaku Hamada, Hiroko Takenaga in Scientific Reports (2021)

  2. Article

    Open Access

    Skeletal open bite with amelogenesis imperfecta treated with compression osteogenesis: a case report

    We successfully treated a 37-year-old male who had skeletal open bite with severe amelogenesis imperfecta (AI) with orthodontics, compression osteogenesis, and prosthodontics.

    Hiroki Mori, Takashi Izawa, Hitoshi Mori, Keiichiro Watanabe in Head & Face Medicine (2019)

  3. No Access

    Article

    Amelotin gene expression is temporarily being upregulated at the initiation of apoptosis induced by TGFβ1 in mouse gingival epithelial cells

    Amelotin (AMTN) is expressed and secreted by ameloblasts in the maturation stage of amelogenesis and persist with low levels in the junctional epithelium (JE) of erupted teeth. The purpose of this study is to ...

    Yohei Nakayama, Sari Matsui, Keisuke Noda, Mizuho Yamazaki, Yasunobu Iwai in Apoptosis (2016)

  4. No Access

    Article

    The Effectiveness of Human Parathyroid Hormone and Low-Intensity Pulsed Ultrasound on the Fracture Healing in Osteoporotic Bones

    Osteoporotic fracture has become a major public health problem, and until today, the treatments available are not satisfactory. While there is growing evidence to support the individual treatment of parathyroi...

    Karima Q. Mansjur, Shingo Kuroda, Takashi Izawa in Annals of Biomedical Engineering (2016)