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  1. Article

    Open Access

    Circulating activated protein C levels are not increased in septic patients treated with recombinant human soluble thrombomodulin

    Recombinant human soluble thrombomodulin (rTM) has been used for the treatment of disseminated intravascular coagulation in Japan, and an international phase III clinical trial for rTM is currently in progress...

    Takuro Arishima, Takashi Ito, Tomotsugu Yasuda, Nozomi Yashima in Thrombosis Journal (2018)

  2. Article

    Open Access

    Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia

    We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type ...

    Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar in Scientific Reports (2018)

  3. No Access

    Chapter

    Monitoring of Brain Oxygenation During and After Cardiopulmonary Resuscitation: A Prospective Porcine Study

    This study aimed to evaluate the usefulness of near-infrared time-resolved spectroscopy (TRS) for the monitoring of post-resuscitation encephalopathy. Cardiac arrest (CA) was induced in pigs by electrical stim...

    Yasuyuki Kakihana, Chinatsu Kamikokuryo, Hiroaki Furubeppu in Oxygen Transport to Tissue XL (2018)

  4. No Access

    Chapter and Conference Paper

    Non-invasive Monitoring of Hepatic Oxygenation Using Time-Resolved Spectroscopy

    The aim of the present study was to investigate whether changes in hepatic oxygenation can be detected by time-resolved spectroscopy (TRS) placed on the skin surface above the liver. METHODS: With approval of ...

    Tomotsugu Yasuda, Keiji Yamaguchi, Takahiro Futatsuki in Oxygen Transport to Tissue XXXVII (2016)