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    Article

    Farrerol maintains the contractile phenotype of VSMCs via inactivating the extracellular signal-regulated protein kinase 1/2 and p38 mitogen-activated protein kinase signaling

    Farrerol, a dihydroflavone isolated from Rhododendron dauricum L., can inhibit vascular smooth muscle cell (VSMC) proliferation and exert a protective effect on H2O2-induced vascular endothelial cells injury. In ...

    Enli Liu, Shasha Shi, Jie Li, Rui Ge, Taigang Liang… in Molecular and Cellular Biochemistry (2020)

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    Article

    3D-QSAR studies of 8-substituted chromen-4-one-2-carboxylic acid derivatives as potent agonists for the orphan G protein-coupled receptor 35

    GPR35, an orphan G protein-coupled receptor, has attracted much attention as a novel therapeutic target for the treatment of diabetes, hypertension, etc. Recently, 8-substituted chromen-4-one-2-carboxylic acid...

    Taigang Liang, Chaoqun Yan, Li Yang, Mengnan Hu… in Medicinal Chemistry Research (2015)