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    Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model

    Brain metastasis is a common complication in melanoma patients with BRAF and NRAS mutations and has a poor prognosis. Although BRAF inhibitors are clinically approved, their poor brain penetration limits their...

    Yu-Yon Kim, Hyun** Park, Taehun Song, Kyung** Choi… in Clinical & Experimental Metastasis (2023)