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Histamine stimulates human lung fibroblast migration

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  1. Article

    Open Access

    Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer

    Transforming growth factor (TGF)-β plays a pivotal role in cancer progression through regulating cancer cell proliferation, invasion, and remodeling of the tumor microenvironment. Cancer-associated fibroblasts...

    Masafumi Horie, Akira Saito, Satoshi Noguchi, Yoko Yamaguchi in BMC Cancer (2014)

  2. Article

    Open Access

    TGF-β1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels

    Apoptosis of fibroblasts may be key for the removal of cells following repair processes. Contraction of three-dimensional collagen gels is a model of wound healing and remodeling. Here two potent inducers of c...

    Tetsu Kobayashi, **angde Liu, Hui Jung Kim, Tadashi Kohyama in Respiratory Research (2005)

  3. Article

    Fibroblasts and monocyte macrophages contract and degrade three-dimensional collagen gels in extended co-culture

    Inflammatory cells are believed to play a prominent role during tissue repair and remodeling. Since repair processes develop and mature over extended time frames, the present study was designed to evaluate the...

    Yunkui Zhu, C Magnus Sköld, **angde Liu, Hangjun Wang in Respiratory Research (2001)

  4. Article

    Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gels

    Extended culture of monocytes and fibroblasts in three-dimensional collagen gels leads to degradation of the gels (see linked study in this issue, "Fibroblasts and monocytes contract and degrade three-dimensio...

    Yunkui Zhu, **angde Liu, C Magnus Sköld, Hangjun Wang in Respiratory Research (2001)