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Article
Open AccessDisparate metabolic response to fructose feeding between different mouse strains
Diets enriched in fructose (FR) increase lipogenesis in the liver, leading to hepatic lipid accumulation and the development of insulin resistance. Previously, we have shown that in contrast to other mouse str...
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Article
Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding
Metabolic disorders are commonly investigated using knockout and transgenic mouse models. A variety of mouse strains have been used for this purpose. However, mouse strains can differ in their inherent propens...
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Article
Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes
The aim of this study was to use lipidomics to determine if the lipid composition of apolipoprotein-B-containing lipoproteins is modified by dyslipidaemia in type 2 diabetes and if any of the identified change...
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Article
Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle
Insulin resistance in skeletal muscle is strongly associated with lipid oversupply, but the intracellular metabolites and underlying mechanisms are unclear. We therefore sought to identify the lipid intermedia...
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Article
Effects of dietary cholesterol restriction in a feline model of Niemann–Pick type C disease
A feline model of Niemann–Pick disease type C (NPC) was employed to evaluate the effect of dietary cholesterol restriction on progression of disease. Two NPC-affected treated cats were fed a cholesterol-restri...
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Article
The phase transition in wet α-keratin fibres above 100 °C
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Article
Proceedings of the Society for Psychical Research
A BOOK entitled “Phantasms of the Living,” by Edmund Gurney, F. W. H. Myers, and Frank Podmore, was published in 1886. Under this title were included all experiences where there was reason to suppose that the ...