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Article
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy
Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients. Somatic gene editing by sequence-specific nucleases of...
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Chapter and Conference Paper
Safety and light integration of alternative powertrains with innovative material concepts
Parallel to the development of the automobile with combustion engines at the end of the 19th century, researchers also developed successfully on electric vehicles. As two substantial examples Werner von Siemen...
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Article
Small Multiple Fixed-Point Cell as Calibration Reference for a Dry Block Calibrator
A small multiple fixed-point cell (SMFPC) was designed to be used as in situ calibration reference of the internal temperature sensor of a dry block calibrator, which would allow its traceable calibration to t...
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Article
Open AccessHuman testicular peritubular cells secrete pigment epithelium-derived factor (PEDF), which may be responsible for the avascularity of the seminiferous tubules
Male fertility depends on spermatogenesis, which takes place in the seminiferous tubules of the testis. This compartment is devoid of blood vessels, which are however found in the wall of the seminiferous tubu...
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Article
Temperature-Dependent Dynamic Behavior of Process Temperature Sensors
For a number of applications in control and safety value monitoring, a profound knowledge of the dynamic behavior of process temperature sensors is of great importance. Sensor test procedures and model identif...
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Article
Dry Block Calibrator Using Heat Flux Sensors and an Adiabatic Shield
The main problems of conventional dry block calibrators are axial temperature gradients and calibration results which are strongly influenced by the geometry and the thermal properties of the thermometers unde...
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Article
Open AccessReadthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive phase, which ultimately ends with menopause in women. These processes are regula...
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Article
Proteome research based on modern liquid chromatography – tandem mass spectrometry: separation, identification and quantification
Recent developments of new generations of mass spectrometers and improvements in the field of chromatography have revolutionized protein analytics. Particularly the combination of liquid chromatography as a se...
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Article
Hepatosplenomegalie, makulöse Effloreszenzen, Thrombozytopenie bei einem Neugeborenen
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Chapter
Peptide-induced antibodies as a tool to link genomes and proteomes
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Article
Qualitätsmanagement
Qualitätsmanagement (QM) ist ein neuer methodischer Zugang zur Qualitätsverbesserung in Einrichtungen des Gesundheitswesens. QM läßt sich als eine prozeßorientierte, umfassende, selbstverantwortliche Unternehm...
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Article
Intrakavernöse Phenylephrininjektion bei pharmakologisch induzierter prolongierter Erektion
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Chapter
Computer-aided similarity and identify search with a FTIR library of surfactants and surfactant mixtures
A digitized library of about 1100 standardized FTIR spectra of surfactants and related materials was evaluated with Lowry-Huppler algorithms and a combination algorithm specially developed for the detection of th...
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Article
Abstracts
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Chapter and Conference Paper
Ergebnisse der Keratoplastik wegen bullöser Keratopathie bei Pseudophakie
121 Keratoplastiken, die von Januar 1980 bis Juli 1993 wegen bullöser Keratopathie bei Pseudophakie operiert wurden, werden retrospektiv analysiert.
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Chapter and Conference Paper
Current Diagnostic Procedures of Rabies and Related Viruses
The usefulness of fluorescent antibody techniques (FAT) for identifying rabies antigen in tissue of infected animals and man was demonstrated by Goldwasser and Kissling (1958). In the following ten years this ...
