3 Result(s)
within
T. A. Hughes
Biomedicine
-
Article
Open AccessCarcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting
Colorectal cancer-specific biomarkers have been used as molecular targets for fluorescent intra-operative imaging, targeted PET/MRI, and selective cytotoxic drug delivery yet the selection of biomarkers used i...
-
Article
Open AccessDichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells
Cancer cells are highly dependent on glycolysis. Our aim was to determine if switching metabolism from glycolysis towards mitochondrial respiration would reduce growth preferentially in colorectal cancer cells...
-
Article
Open AccessCombined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity
Increased eukaryotic translation initiation factor 4E (eIF4E) expression occurs in many cancers, and makes fundamental contributions to carcinogenesis by stimulating the expression of cancer-related genes at p...
