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Article
Weak MGMT gene promoter methylation confers a clinically significant survival benefit in patients with newly diagnosed glioblastoma: a retrospective cohort study
Quantitative methylation specific PCR (qMSP) is a frequently used technique to assess MGMT gene promoter methylation in glioblastoma patients. The optimal technical cut-off value to distinguish methylated from un...
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Article
Omega-3 fatty acids: physiology, biological sources and potential applications in supportive cancer care
The impact of the Western diet on chronic diseases, such as cancer, has been well recognized. Dietary saturated and trans fatty acids have been found to play a negative role in obesity, heart disease, diabetes an...
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Article
Open AccessChromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?
The association between chromosomal radiosensitivity and genetic predisposition to head and neck cancer was investigated in this study. In all, 101 head and neck cancer patients and 75 healthy control individu...
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Article
Open AccessRecombinant human erythropoietin α modulates the effects of radiotherapy on colorectal cancer microvessels
Recent data suggest that recombinant human erythropoietin (rhEPO) modulates tumour growth and therapy response. The purpose of the present study was to examine the modulation of radiotherapy (RT) effects on tu...
