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Article
Open AccessOverexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner
Overexpression the KCNJ3, a gene that encodes subunit 1 of G-protein activated inwardly rectifying K+ channel (GIRK1) in the primary tumor has been found to be associated with reduced survival times and increased...
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Article
Open AccessMiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
MicroRNAs (miRNAs) regulate the biological properties of colorectal cancer (CRC) cells and might serve as potential prognostic factors and therapeutic targets. In this study, we therefore globally profiled miR...
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Article
Open AccessProlactin receptor is a negative prognostic factor in patients with squamous cell carcinoma of the head and neck
The influence of human prolactin (hPRL) on the development of breast and other types of cancer is well established. Little information, however, exists on the effects of hPRL on squamous cell carcinomas of the...
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Article
Frequency of febrile neutropenia in patients treated with taxane/epirubicine and colony-stimulating growth factors for breast cancer: comparison of filgrastim/lenograstim with pegfilgrastim
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Article
Open AccessRole of prolactin receptor and CD25 in protection of circulating T lymphocytes from apoptosis in patients with breast cancer
Prolactin (PRL) has been reported to inhibit apoptosis in various cell types and to serve as a cofactor in the upregulation of CD25 on T cells during activation. We investigated a possible relation between pro...
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Article
Spontaneous apoptosis of circulating T-lymphocytes and its correlation to their prolactin receptor expression and prolactin plasma levels in patients with breast cancer