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Cu-catalyzed enantioselective allylic alkylation with organolithium reagents

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  1. Article

    Open Access

    A catalytically active oscillator made from small organic molecules

    Oscillatory systems regulate many biological processes, including key cellular functions such as metabolism and cell division, as well as larger-scale processes such as circadian rhythm and heartbeat14. Abiotic ...

    Matthijs ter Harmsel, Oliver R. Maguire, Sofiya A. Runikhina, Albert S. Y. Wong in Nature (2023)

  2. Article

    Open Access

    Catalytic enantioselective addition of organometallics to unprotected carboxylic acids

    Conjugate addition of organometallics to carbonyl based Michael acceptors is a widely used method that allows the building of new carbon-carbon (C-C) bonds and the introduction of chirality in a single step. H...

    **ngchen Yan, Syuzanna R. Harutyunyan in Nature Communications (2019)

  3. Article

    Open Access

    Highly enantioselective catalytic synthesis of chiral pyridines

    General methods to prepare chiral pyridine derivatives are greatly sought after due to their significance in medicinal chemistry. Here, we report highly enantioselective catalytic transformations of poorly rea...

    Ravindra P. Jumde, Francesco Lanza, Tilde Pellegrini in Nature Communications (2017)

  4. Article

    Open Access

    Catalytic enantioselective addition of Grignard reagents to aromatic silyl ketimines

    α-Chiral amines are of significant importance in medicinal chemistry, asymmetric synthesis and material science, but methods for their efficient synthesis are scarce. In particular, the synthesis of α-chiral a...

    Jiawei Rong, Juan F. Collados, Pablo Ortiz, Ravindra P. Jumde in Nature Communications (2016)