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  1. Article

    Open Access

    Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

    In a Phase I study treatment with the serum amyloid P component (SAP) depleter miridesap followed by monoclonal antibody to SAP (dezamizumab) showed removal of amyloid from liver, spleen and kidney in patients...

    Ashutosh Wechalekar, Gunnar Antoni, Wasfi Al Azzam… in BMC Cardiovascular Disorders (2022)

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