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  1. Article

    Open Access

    Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial

    Affinity-optimized T cell receptors can enhance the potency of adoptive T cell therapy. Afamitresgene autoleucel (afami-cel) is a human leukocyte antigen-restricted autologous T cell therapy targeting melanoma...

    David S. Hong, Brian A. Van Tine, Swethajit Biswas, Cheryl McAlpine in Nature Medicine (2023)

  2. No Access

    Article

    Non-glucose metabolism in cancer cells—is it all in the fat?

    Cancer biologists seem to have overlooked tumor metabolism in their research endeavors over the last 80 years of the last century, only to have “rediscovered Warburg” (Warburg et al. 1930; Warburg, Science 123(31...

    Swethajit Biswas, John Lunec, Kim Bartlett in Cancer and Metastasis Reviews (2012)