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Article
Open AccessAutologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial
Affinity-optimized T cell receptors can enhance the potency of adoptive T cell therapy. Afamitresgene autoleucel (afami-cel) is a human leukocyte antigen-restricted autologous T cell therapy targeting melanoma...
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Article
Non-glucose metabolism in cancer cells—is it all in the fat?
Cancer biologists seem to have overlooked tumor metabolism in their research endeavors over the last 80 years of the last century, only to have “rediscovered Warburg” (Warburg et al. 1930; Warburg, Science 123(31...