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  1. Article

    Open Access

    Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge

    A key feature of metabolic health is the ability to adapt upon dietary perturbations. Recently, it was shown that metabolic challenge tests in combination with the new generation biomarkers allow the simultane...

    Suzan Wopereis, Johanna H. M. Stroeve, Annette Stafleu in Genes & Nutrition (2017)

  2. Article

    Open Access

    The impact of micronutrient status on health: correlation network analysis to understand the role of micronutrients in metabolic-inflammatory processes regulating homeostasis and phenotypic flexibility

    Vitamins and carotenoids are key micronutrients facilitating the maintenance of health, as evidenced by the increased risk of disease with low intake. Optimal phenotypic flexibility, i.e., the ability to respo...

    Tim J. van den Broek, Bas H. A. Kremer, Marisa Marcondes Rezende in Genes & Nutrition (2017)

  3. Article

    Open Access

    Phenotypic flexibility as a measure of health: the optimal nutritional stress response test

    Nutrition research is struggling to demonstrate beneficial health effects, since nutritional effects are often subtle and long term. Health has been redefined as the ability of our body to cope with daily-life...

    Johanna H. M. Stroeve, Herman van Wietmarschen, Bas H. A. Kremer in Genes & Nutrition (2015)

  4. Article

    Open Access

    The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research

    Micronutrients influence multiple metabolic pathways including oxidative and inflammatory processes. Optimum micronutrient supply is important for the maintenance of homeostasis in metabolism and, ultimately, ...

    Ben van Ommen, Ahmed El-Sohemy, John Hesketh, Jim Kaput in Genes & Nutrition (2010)

  5. Article

    Open Access

    Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies

    The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioacti...

    Ben van Ommen, Jildau Bouwman, Lars O. Dragsted, Christian A. Drevon in Genes & Nutrition (2010)