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  1. Article

    Open Access

    Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor

    This study investigated the inhibitory effect of arctigenin, a novel anti-inflammatory lignan, on prostate cancer in obese conditions both in vitro and in vivo. In vitro obese models were established by co-cultur...

    Qiongyu Hao, Tanya Diaz, Alejandro del Rio Verduzco, Clara E. Magyar in Scientific Reports (2020)

  2. Article

    Open Access

    Pomegranate Juice and Extract Consumption Increases the Resistance to UVB-induced Erythema and Changes the Skin Microbiome in Healthy Women: a Randomized Controlled Trial

    In vitro and animal studies have demonstrated that topical application and oral consumption of pomegranate reduces UVB-induced skin damage. We therefore investigated if oral pomegranate consumption will reduce ph...

    Susanne M. Henning, Jie** Yang, Ru-Po Lee, Jianjun Huang, Mark Hsu in Scientific Reports (2019)

  3. Article

    Open Access

    Health benefit of vegetable/fruit juice-based diet: Role of microbiome

    The gut microbiota is an important contributor to human health. Vegetable/fruit juices provide polyphenols, oligosaccharides, fiber and nitrate (beet juice), which may induce a prebiotic-like effect. Juice-bas...

    Susanne M. Henning, Jie** Yang, Paul Shao, Ru-Po Lee, Jianjun Huang in Scientific Reports (2017)

  4. Article

    Open Access

    Ambient Ultrafine Particle Ingestion Alters Gut Microbiota in Association with Increased Atherogenic Lipid Metabolites

    Ambient particulate matter (PM) exposure is associated with atherosclerosis and inflammatory bowel disease. Ultrafine particles (UFP, dp < 0.1–0.2 μm) are redox active components of PM. We hypothesized that orall...

    Rongsong Li, Jie** Yang, Arian Saffari, Jonathan Jacobs in Scientific Reports (2017)