3 Result(s)
within
Susana Boluda
Neurosciences
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Article
Open AccessPathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice
Alzheimer's disease (AD) is characterized by intracerebral accumulations of extracellular amyloid-β (Aβ) plaques and intracellular tau pathology that spread in the brain. Three types of tau lesions occur in th...
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Article
Open AccessTransmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate
Amyloid-β (Aβ) pathology transmission has been described in patients following iatrogenic exposure to compounds contaminated with Aβ proteins. It can induce cerebral Aβ angiopathy resulting in brain hemorrhage...
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Article
Open AccessInduction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued from human brains
In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as af...
