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    Alzheimer’s senile plaque as shown by microcryodissection, a new technique for dissociating tissue structures

    Extracellular accumulation of Aβ peptides and intracellular aggregation of hyperphosphorylated tau proteins are the two hallmark lesions of Alzheimer disease (AD). The senile plaque is made of a core of extrac...

    Manon Thierry, Serge Marty, Susana Boluda in Journal of Neural Transmission (2017)