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Article
The Heritability of Gender Identity Disorder in a Child and Adolescent Twin Sample
The heritability and prevalence of the gender identity disorder (GID) was examined, as well as its comorbidity with separation anxiety and depression, in a nonretrospective study of child and adolescent twins....
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Article
Contributions of Genes and Environments to Stability and Change in Externalizing and Internalizing Problems During Elementary and Middle School
We examined longitudinally collected behavioral reports by teachers on a unique twin sample at the ages of 7, 8, 9, 10, 11, and 12 years. As twin and adoption studies implicate the role of genetic influence on...
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Article
Genetic and Environmental Vulnerabilities Underlying Adolescent Substance Use and Problem Use: General or Specific?
Are genetic and environmental risks for adolescent substance use specific to individual substances or general across substance classes? We examined this question in 645 monozygotic twin pairs, 702 dizygotic tw...
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Article
Genes and Developmental Stabiltiy of Aggressive Behavior Problems at Home and School in a Community Sample of Twins Aged 7–12
Though behavioral genetic studies of aggression have implicated heritable and environmental factors, there is limited understanding of how these factors influence aggression across different settings and over ...
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Article
Externalizing Behaviors are Associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster
There is strong evidence for shared genetic factors contributing to childhood externalizing disorders and substance abuse. Externalizing disorders often precede early substance experimentation, leading to the ...
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Article
Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample
Behavioral disinhibition (BD) is a quantitative measure designed to capture the heritable variation encompassing risky and impulsive behaviors. As a result, BD represents an ideal target for discovering genet...
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Article
Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders
Executive functions (EFs) have been proposed as an endophenotype for psychopathology because EF deficits are associated with most psychiatric disorders. To examine this hypothesis, we derived polygenic risk sc...