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Article
Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample
Behavioral disinhibition (BD) is a quantitative measure designed to capture the heritable variation encompassing risky and impulsive behaviors. As a result, BD represents an ideal target for discovering genet...
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Article
Population Frequencies of the Triallelic 5HTTLPR in Six Ethnicially Diverse Samples from North America, Southeast Asia, and Africa
Genetic differences between populations are potentially an important contributor to health disparities around the globe. As differences in gene frequencies influence study design, it is important to have a th...
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Article
Simple Sequence Repeats in the National Longitudinal Study of Adolescent Health: An Ethnically Diverse Resource for Genetic Analysis of Health and Behavior
Simple sequence repeats (SSRs) are one of the earliest available forms of genetic variation available for analysis and have been utilized in studies of neurological, behavioral, and health phenotypes. Although...
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Article
Is the Gene-Environment Interaction Paradigm Relevant to Genome-Wide Studies? The Case of Education and Body Mass Index
This study uses data from the Framingham Heart Study to examine the relevance of the gene-environment interaction paradigm for genome-wide association studies (GWAS). We use completed college education as our ...
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Article
Stable Genes and Changing Environments: Body Mass Index Across Adolescence and Young Adulthood
The transition between adolescence and young adulthood is a developmentally sensitive time where children are at an increased risk for becoming overweight and develo** obesity. Twin studies have reported tha...
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Article
The Association Between Conduct Problems and Maltreatment: Testing Genetic and Environmental Mediation
It is often assumed that childhood maltreatment causes conduct problems via an environmentally mediated process. However, the association may be due alternatively to either a nonpassive gene-environment correl...
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Article
The Developmental Etiology of High IQ
The genetic and environmental trends in IQ development were assessed in 483 same-sex twin pairs in the Colorado longitudinal twin study using maximum-likelihood model-fitting analysis. The twins were assessed ...
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Article
Investigation of Genetically Mediated Child Effects on Maltreatment
Theory and empirical evidence suggest that children’s genetically influenced characteristics help to shape the environments they experience, including the parenting they ‘receive’. The extent of these genetica...
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Article
Do Schools Moderate the Genetic Determinants of Smoking?
This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our ...
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Article
Genes and Developmental Stabiltiy of Aggressive Behavior Problems at Home and School in a Community Sample of Twins Aged 7–12
Though behavioral genetic studies of aggression have implicated heritable and environmental factors, there is limited understanding of how these factors influence aggression across different settings and over ...
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Article
Relationship between Adolescent Marijuana Use and Young Adult Illicit Drug Use
We examined three components of the “gateway theory” in relation to marijuana use: (1) whether adolescent marijuana use predicts young adult drug use, (2) whether this association persists when controlling for...
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Article
Contributions of Genes and Environments to Stability and Change in Externalizing and Internalizing Problems During Elementary and Middle School
We examined longitudinally collected behavioral reports by teachers on a unique twin sample at the ages of 7, 8, 9, 10, 11, and 12 years. As twin and adoption studies implicate the role of genetic influence on...
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Article
Genoty** of Three Single Nucleotide Polymorphisms Following Whole Genome Preamplification of DNA Collected from Buccal Cells
Collection of genomic DNA from buccal cells is a simple and convenient procedure for genoty** individuals. One disadvantage is that the amount of genomic DNA may be inadequate for genoty** projects that re...