49 Result(s)
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Article
Circulating vitamin D and breast cancer risk: an international pooling project of 17 cohorts
Laboratory and animal research support a protective role for vitamin D in breast carcinogenesis, but epidemiologic studies have been inconclusive. To examine comprehensively the relationship of circulating 25-...
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Article
Associations of depression status with plasma levels of candidate lipid and amino acid metabolites: a meta-analysis of individual data from three independent samples of US postmenopausal women
Recent animal and small clinical studies have suggested depression is related to altered lipid and amino acid profiles. However, this has not been examined in a population-based sample, particularly in women. ...
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Article
Posttraumatic stress disorder and development of premenstrual syndrome in a longitudinal cohort of women
We examined the association between posttraumatic stress disorder (+PTSD) symptoms and incident premenstrual syndrome (PMS) in a longitudinal study with 14 years follow-up of 2924 women aged 27–44. Compared to...
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Article
Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women
We examined the association of plasma B-vitamins and metabolites, and related genetic variants, with risk of breast cancer among predominantly premenopausal women.
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Article
Pre-diagnostic sex hormone levels and survival among breast cancer patients
Higher levels of circulating sex steroid hormones are associated with increased breast cancer risk, though their association with prognosis remains unclear. We evaluated the association between circulating sex...
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Article
Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues
In post-menopausal women, high body mass index (BMI) is an established breast cancer risk factor and is associated with worse breast cancer prognosis. We assessed the associations between BMI and gene expressi...
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Article
Circulating prolactin concentrations and risk of type 2 diabetes in US women
Prolactin, a multifunctional hormone, is involved in regulating insulin sensitivity and glucose homeostasis in experimental studies. However, whether circulating concentrations of prolactin are associated with...
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Article
Carbohydrate and fiber intake and the risk of premenstrual syndrome
Women with premenstrual syndrome (PMS) are encouraged to reduce sugar and increase fiber intake to reduce symptoms. However, research supporting these recommendations is limited, and their role in PMS developm...
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Article
Circulating Hormones and Mammographic Density in Premenopausal Women
Prior research suggests that several endogenous hormones in premenopausal women are associated with breast cancer risk; however, few studies have evaluated associations of endogenous hormones with mammographic...
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Article
Breast cancer risk prediction: an update to the Rosner–Colditz breast cancer incidence model
To update and expand the Rosner–Colditz breast cancer incidence model by evaluating the contributions of more recently identified risk factors as well as predicted percent mammographic density (MD) to breast c...
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Article
Extensions of the Rosner-Colditz breast cancer prediction model to include older women and type-specific predicted risk
A breast cancer risk prediction rule previously developed by Rosner and Colditz has reasonable predictive ability. We developed a re-fitted version of this model, based on more than twice as many cases now inc...
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Article
Accounting for individualized competing mortality risks in estimating postmenopausal breast cancer risk
Accurate risk assessment is necessary for decision-making around breast cancer prevention. We aimed to develop a breast cancer prediction model for postmenopausal women that would take into account their indiv...
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Article
Plasma fluorescent oxidation products and risk of estrogen receptor-negative breast cancer in the Nurses’ Health Study and Nurses’ Health Study II
Findings from epidemiologic studies of oxidative stress biomarkers and breast cancer have been mixed, although no studies have focused on estrogen receptor-negative (ER−) tumors which may be more strongly asso...
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Article
Healthy dietary patterns and risk of breast cancer by molecular subtype
We examined associations between dietary quality indices and breast cancer risk by molecular subtype among 100,643 women in the prospective Nurses’ Health Study (NHS) cohort, followed from 1984 to 2006. Dieta...
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Article
Alcohol Consumption and Urinary Estrogens and Estrogen Metabolites in Premenopausal Women
In a cross-sectional analysis, we evaluated the associations of usual total alcohol and wine intake with a comprehensive profile of mid-luteal phase urinary estrogens and estrogen metabolites (referred to join...
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Article
Alcohol Consumption and Risk of Breast Cancer by Tumor Receptor Expression
In epidemiologic studies, alcohol consumption appears more strongly associated with risk of estrogen receptor (ER)-positive than ER-negative breast cancer. However, this association has not been assessed by ot...
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Article
Open AccessThe association of body size in early to mid-life with adult urinary 6-sulfatoxymelatonin levels among night shift health care workers
Adult body mass index (BMI) has been associated with urinary melatonin levels in humans; however, whether earlier-life body size is associated with melatonin, particularly among night shift workers, remains un...
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Article
Open AccessShort-term weight gain and breast cancer risk by hormone receptor classification among pre- and postmenopausal women
Obesity is well established as a cause of postmenopausal breast cancer incidence and mortality. In contrast, adiposity in early life reduces breast cancer incidence. However, whether short-term weight change i...
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Article
The Relationship Between Bilateral Oophorectomy and Plasma Hormone Levels in Postmenopausal Women
Oophorectomy prior to natural menopause reduces breast cancer risk. We evaluated whether timing of oophorectomy (during premenopause vs. postmenopause) or hysterectomy was associated with hormone levels, speci...
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Article
Premenopausal plasma 25-hydroxyvitamin D, mammographic density, and risk of breast cancer
Epidemiologic evidence for an association between plasma 25-hydroxyvitamin D [25(OH)D] and breast cancer is inconsistent. Data are especially limited for premenopausal women and for associations with mammograp...
