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  1. Article

    Open Access

    miR-34a regulates mesangial cell proliferation via the PDGFR-β/Ras-MAPK signaling pathway

    The main pathological characteristic of glomerulonephritis is diffuse mesangial cell proliferation. MiR-34a is associated with the proliferation of various organs and cancer cells. However, the role of miR-34a...

    Dapeng Chen, Ying Li, Yan Mei, Wenjia Geng in Cellular and Molecular Life Sciences (2014)

  2. No Access

    Article

    Impaired autophagic function in rat islets with aging

    Type 2 diabetes is characterized by a deficit in β-cell function and mass, and its incidence increases with age. Autophagy is a highly regulated intracellular process for degrading cytoplasmic components, part...

    Yu Liu, Suozhu Shi, Zhaoyan Gu, Yingzhen Du, Minyan Liu, Shuangtong Yan, Jianjun Gao in AGE (2013)

  3. Article

    Open Access

    Novel mechanism for mesenchymal stem cells in attenuating peritoneal adhesion: accumulating in the lung and secreting tumor necrosis factor α-stimulating gene-6

    We previously found that mesenchymal stem cells (MSCs) injected intravenously could attenuate peritoneal adhesion by secreting tumor necrosis alpha-stimulating gene (TSG)-6, while MSCs injected intraperitoneal...

    Nan Wang, Yeqing Shao, Yan Mei, Li Zhang, Qinggang Li in Stem Cell Research & Therapy (2012)

  4. No Access

    Article

    Age-related changes in the function of autophagy in rat kidneys

    Autophagy is a highly regulated intracellular process for the degradation of cytoplasmic components, especially protein aggregates and damaged organelles. It is essential for maintaining healthy cells. Impaire...

    **g Cui, Xue-Yuan Bai, Suozhu Shi, Shaoyuan Cui, Quan Hong, Guangyan Cai in AGE (2012)