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Article
Open AccessCharacterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling
Organoids culture provides unique opportunities to study human diseases and to complement animal models. Several organs and tissues can be in vitro cultured in 3D structures resembling in vivo tissue organizat...
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Article
Level of tissue differentiation influences the activation of a heat-inducible flower-specific system for genetic containment in poplar (Populus tremula L.)
Differentiation level but not transgene copy number influenced activation of a gene containment system in poplar. Heat treatments promoted CRE gene body meth...
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Article
Open AccessTargeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained
DNA methylation and histone 3 lysine 9 (H3K9) methylation are considered as epigenetic marks that can be inherited through cell divisions. To explore the functional consequences and stability of these modifica...
