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  1. Article

    Open Access

    NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels

    Hydrocephalus is a severe complication of intracerebral hemorrhage with ventricular extension (ICH-IVH) and causes cerebrospinal fluid (CSF) accumulation. The choroid plexus epithelium plays an important role ...

    Zhaoqi Zhang, Qiang Tan, Peiwen Guo, Suna Huang in Journal of Neuroinflammation (2022)

  2. No Access

    Article

    Angiotensin II Inhibits Iron Uptake and Release in Cultured Neurons

    Based on the well-confirmed roles of angiotensin II (ANGII) in iron transport of peripheral organs and cells, the causative link of excess brain iron with and the involvement of ANGII in neurodegenerative diso...

    Yong Liu, Suna Huang, Fang Du, Guang Yang, Li Rong Jiang in Neurochemical Research (2014)

  3. Article

    Open Access

    Clinical relevance of the interleukin 10 promoter polymorphisms in Chinese Han patients with major trauma: genetic association studies

    An excessive inflammatory response is thought to account for the pathogenesis of sepsis and multiple organ dysfunction syndrome (MODS) after severe trauma. The interleukin-10 (IL-10) is a potent anti-inflammat...

    Ling Zeng, Wei Gu, Kehong Chen, Dongpo Jiang, Lianyang Zhang, Dingyuan Du in Critical Care (2009)