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Open AccessAssociation between arterial tortuosity and early neurological deterioration in lenticulostriate artery infarction
Early neurological deterioration (END) in lenticulostriate artery (LSA) infarction is associated with perforating artery hypoperfusion. As middle cerebral artery (MCA) tortuosity may alter hemodynamics, we inv...
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Article
Open AccessIn-stent restenosis and stented-territory infarction after carotid and vertebrobasilar artery stenting
Prognosis after vertebrobasilar stenting (VBS) may differ from that after carotid artery stenting (CAS). Here, we directly compared the incidence and predictors of in-stent restenosis and stented-territory inf...
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Article
Open AccessFactors associated with two different stroke mechanisms in perforator infarctions regarding the shape of arteries
Two different stroke mechanisms are involved in small vessel disease: branch atheromatous disease (BAD) and lipohyalinotic degeneration (LD). We compared mechanisms of stroke in lenticulostriate arteries (LSA)...
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Article
Open AccessPrior intracerebral hemorrhage and white matter hyperintensity burden on recurrent stroke risk
Prior intracerebral hemorrhage (ICH) is associated with increased risk of ischemic stroke. Since white matter hyperintensity (WMH) is associated with ischemic stroke and ICH, this study aimed to evaluate the r...
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Article
Open AccessNewly diagnosed diabetes has high risk for cardiovascular outcome in ischemic stroke patients
We investigated cardiovascular outcomes in ischemic stroke patients with newly diagnosed diabetes mellitus (DM) compared with those of patients with previously known DM and no DM using the glycosylated hemoglo...
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Open AccessBlood pressure variability is related to faster cognitive decline in ischemic stroke patients: PICASSO subanalysis
Blood pressure variability (BPV) is associated with higher cardiovascular morbidity risks; however, its association with cognitive decline remains unclear. We investigated whether higher BPV is associated with...
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Article
Open AccessPromoter methylation changes in ALOX12 and AIRE1: novel epigenetic markers for atherosclerosis
Atherosclerosis is the main cause of cardiovascular diseases such as ischemic stroke and coronary heart disease. Gene-specific promoter methylation changes have been suggested as one of the causes underlying t...
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Open AccessComparison of outcomes after carotid endarterectomy between type 2 diabetic and non-diabetic patients with significant carotid stenosis
We aimed to compare early and late outcomes after carotid endarterectomy (CEA) between Korean type 2 diabetic and non-diabetic patients and to investigate the impact of diabetes on the overall incidence of car...
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Open AccessA phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis
18F-GP1 is a novel positron emission tomography (PET) tracer that targets glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the feasibility of directly imaging acute arte....
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Open AccessRisk of major adverse cardiovascular events in subjects with asymptomatic mild carotid artery stenosis
This study aimed to test the hypothesis that the risk of major adverse cardiovascular events (MACE) is similar for subjects with asymptomatic mild and moderate carotid artery stenosis (CAS). We enrolled a tota...
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Open AccessImpact of diabetes duration and degree of carotid artery stenosis on major adverse cardiovascular events: a single-center, retrospective, observational cohort study
We aimed to investigate the impact of diabetes duration and carotid artery stenosis (CAS) on the occurrence of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) withou...