15 Result(s)
within
Stylianos Lefkopoulos
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Article
Scarless healing
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Extending blastoid potential
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A human peri-gastrulation model
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Prioritizing diversity will help all of us
Kelly Stevens is an associate professor in the departments of Bioengineering and Laboratory Medicine & Pathology at the University of Washington. We spoke with her and discussed her work, her views on diversit...
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Enhancing reproducibility in human stem cell research
In June 2023, the International Society for Stem Cell Research (ISSCR) released a report detailing standards for human stem cell research. We spoke to the co-chair...
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Tackling neurodegeneration
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Now is the greatest time to be in it
Daylon James is an associate professor at Weill Cornell Medicine in New York, where his work focuses on reproductive biology and cell-based approaches for treating infertility. Arun Sharma is an assistant prof...
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Nuclear transport times ZGA onset
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Senescence esca** immunity
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Roles for H3K9me3 in human embryos
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Pushing chromatin to totipotency
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Open AccessPublisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
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Open AccessChemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
Haematopoietic stem cells (HSCs) are normally quiescent, but have evolved mechanisms to respond to stress. Here, we evaluate haematopoietic regeneration induced by chemotherapy. We detect robust chromatin reor...
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Open AccessSynonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency
Deficiency of the transcription factor GATA2 is a highly penetrant genetic disorder predisposing to myelodysplastic syndromes (MDS) and immunodeficiency. It has been recognized as the most common cause underly...
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Open AccessA metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlap** pathways
The H2.0-like homeobox transcription factor (HLX) regulates hematopoietic differentiation and is overexpressed in Acute Myeloid Leukemia (AML), but the mechanisms underlying these functions remain unclear. We ...
