4 Result(s)
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Article
Open AccessThe small G-protein RalA promotes progression and metastasis of triple-negative breast cancer
Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part...
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Article
Open AccessGenomic features of rapid versus late relapse in triple negative breast cancer
Triple-negative breast cancer (TNBC) is a heterogeneous disease and we have previously shown that rapid relapse of TNBC is associated with distinct sociodemographic features. We hypothesized that rapid versus ...
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Article
Open AccessNEDD4 expression is associated with breast cancer progression and is predictive of a poor prognosis
A role for neural precursor cell-expressed developmentally downregulated gene 4 (NEDD4) in tumorigenesis has been suggested. However, information is lacking on its role in breast tumor biology. The purpose of ...
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Article
Open AccessFollistatin is a metastasis suppressor in a mouse model of HER2-positive breast cancer
Follistatin (FST) is an intrinsic inhibitor of activin, a member of the transforming growth factor-β superfamily of ligands. The prognostic value of FST and its family members, the follistatin-like (FSTL) prot...
