10 Result(s)
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Article
Open AccessPlasma metabolites in childhood Burkitt lymphoma cases and cancer-free controls in Uganda
Burkitt lymphoma (BL) is an aggressive non-Hodgkin lymphoma associated with Plasmodium falciparum and Epstein-Barr virus, both of which affect metabolic pathways. The metabolomic patterns of BL is unknown.
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Article
Open AccessObservational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study
The association of fitness with cancer risk is not clear.
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Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men
Apolipoprotein E (APOE) allelic variation is associated with differences in overall circulating lipids and risks of major health outcomes. Lipid profiling provides the opportunity for a more detailed description ...
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Article
Open AccessAlcohol and oestrogen metabolites in postmenopausal women in the Women’s Health Initiative Observational Study
Alcohol consumption is associated with an increased risk of several cancers. Potential mechanisms include altered oestrogen metabolism. Parent oestrogens metabolise into alternate pathways of oestrogen metabol...
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Habitual sleep and human plasma metabolomics
Sleep plays an important role in cardiometabolic health. The sleep-wake cycle is partially driven by the endogenous circadian clock, which governs a range of metabolic pathways. The association between sleep a...
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Open AccessSerum metabolomic profiling of prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial
Two recent metabolomic analyses found serum lipid, energy, and other metabolites related to aggressive prostate cancer risk up to 20 years prior to diagnosis.
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Article
Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults
Metabolomic studies have identified several metabolites associated with type 2 diabetes (T2D) in populations of European ancestry. East Asians, a population of particular susceptibility to T2D, were generally ...
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1-Stearoylglycerol is associated with risk of prostate cancer: results from a serum metabolomic profiling analysis
Although prostate cancer is the most commonly diagnosed cancer among men in developed populations, recent recommendations against routine prostate-specific antigen screening have cast doubt on its utility for ...
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Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studies
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Article
Human metabolic correlates of body mass index
A high body mass index (BMI) is a major risk factor for several chronic diseases, but the biology underlying these associations is not well-understood. Dyslipidemia, inflammation, and elevated levels of growth...
