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Article
Open AccessPlasma metabolites in childhood Burkitt lymphoma cases and cancer-free controls in Uganda
Burkitt lymphoma (BL) is an aggressive non-Hodgkin lymphoma associated with Plasmodium falciparum and Epstein-Barr virus, both of which affect metabolic pathways. The metabolomic patterns of BL is unknown.
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Article
Open AccessObservational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study
The association of fitness with cancer risk is not clear.
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Article
Lipidomics and pancreatic cancer risk in two prospective studies
Pancreatic ductal carcinoma (PDAC) is highly fatal with limited understanding of mechanisms underlying its carcinogenesis. We comprehensively investigated whether lipidomic measures were associated with PDAC i...
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Article
Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men
Apolipoprotein E (APOE) allelic variation is associated with differences in overall circulating lipids and risks of major health outcomes. Lipid profiling provides the opportunity for a more detailed description ...
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Article
Open AccessMetabolomics and breast cancer: scaling up for robust results
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Article
Correction to: Breast cancer risk in relation to plasma metabolites among Hispanic and African American women
In the original publication of the article, the sixth author name Krita A. Zanetti was mistakenly included as co-author. The corrected author group is given in the correction article. The original article has ...
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Article
Breast cancer risk in relation to plasma metabolites among Hispanic and African American women
The metabolic etiology of breast cancer has been explored in the past several years using metabolomics. However, most of these studies only included non-Hispanic White individuals.
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Article
Open AccessMetabolic profiling of adherence to diet, physical activity and body size recommendations for cancer prevention
Maintaining a healthy body weight, eating well and being physically active lowers cancer risk by 30%. However, the biology underlying these relationships is not well understood. We examined cross-sectional ass...
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Article
Open AccessMetabolomic profiles in breast cancer:a pilot case-control study in the breast cancer family registry
Metabolomics is emerging as an important tool for detecting differences between diseased and non-diseased individuals. However, prospective studies are limited.
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Article
Open AccessAlcohol and oestrogen metabolites in postmenopausal women in the Women’s Health Initiative Observational Study
Alcohol consumption is associated with an increased risk of several cancers. Potential mechanisms include altered oestrogen metabolism. Parent oestrogens metabolise into alternate pathways of oestrogen metabol...
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Article
Habitual sleep and human plasma metabolomics
Sleep plays an important role in cardiometabolic health. The sleep-wake cycle is partially driven by the endogenous circadian clock, which governs a range of metabolic pathways. The association between sleep a...
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Article
Body mass index, physical activity, and television time in relation to mortality risk among endometrial cancer survivors in the NIH-AARP Diet and Health Study cohort
Endometrial cancer (EC) survivors are the second largest group of female cancer survivors in the USA, with high prevalence of obesity and physical inactivity. While higher pre-diagnosis body mass index (BMI) h...
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Article
Open AccessSerum metabolomic profiling of prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial
Two recent metabolomic analyses found serum lipid, energy, and other metabolites related to aggressive prostate cancer risk up to 20 years prior to diagnosis.
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Article
Open AccessImpact of changes in television viewing time and physical activity on longevity: a prospective cohort study
Television viewing is a highly prevalent sedentary behavior among older adults, yet the mortality risks associated with hours of daily viewing over many years and whether increasing or decreasing viewing time ...
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Article
Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults
Metabolomic studies have identified several metabolites associated with type 2 diabetes (T2D) in populations of European ancestry. East Asians, a population of particular susceptibility to T2D, were generally ...
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Article
1-Stearoylglycerol is associated with risk of prostate cancer: results from a serum metabolomic profiling analysis
Although prostate cancer is the most commonly diagnosed cancer among men in developed populations, recent recommendations against routine prostate-specific antigen screening have cast doubt on its utility for ...
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Article
Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studies
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Article
Human metabolic correlates of body mass index
A high body mass index (BMI) is a major risk factor for several chronic diseases, but the biology underlying these associations is not well-understood. Dyslipidemia, inflammation, and elevated levels of growth...
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Article
The association between frequency of vigorous physical activity and hepatobiliary cancers in the NIH-AARP Diet and Health Study
Despite a potential preventive effect of physical activity on hepatobiliary cancer, little information is available on the relation between the two. We studied the association between frequency of vigorous phy...
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Article
Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer
To investigate, among women with breast cancer, how postdiagnosis diet quality and the combination of diet quality and recreational physical activity are associated with prognosis.
