15 Result(s)
within
Stephen S. Moore
Life Sciences
Plant Genetics and Genomics
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Article
Open AccessGenome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle
Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genom...
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Article
Open AccessHarnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)
Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model s...
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Article
Open AccessNon-synonymous mutations mapped to chromosome X associated with andrological and growth traits in beef cattle
Previous genome-wide association analyses identified QTL regions in the X chromosome for percentage of normal sperm and scrotal circumference in Brahman and Tropical Composite cattle. These traits are importan...
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Article
Open AccessEvidence for positive selection of taurine genes within a QTL region on chromosome X associated with testicular size in Australian Brahman cattle
Previous genome-wide association studies have identified significant regions of the X chromosome associated with reproductive traits in two Bos indicus-influenced breeds: Brahman cattle and Tropical Composites. T...
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Article
Open AccessWhole-genome resequencing of Hanwoo (Korean cattle) and insight into regions of homozygosity
Hanwoo (Korean cattle), which originated from natural crossbreeding between taurine and zebu cattle, migrated to the Korean peninsula through North China. Hanwoo were raised as draft animals until the 1970s wi...
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Open AccessGenome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle
Linkage disequilibrium (LD) between genes at linked or independent loci can occur at gametic and zygotic levels known asgametic LD and zygotic LD, respectively. Gametic LD is well known for its roles in fine-s...
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Open AccessWhole genome resequencing of black Angus and Holstein cattle for SNP and CNV discovery
One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic vari...
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Article
Open AccessA 2cM genome-wide scan of European Holstein cattle affected by classical BSE
Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion p...
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Article
Open AccessHigh density linkage disequilibrium maps of chromosome 14 in Holstein and Angus cattle
Linkage disequilibrium (LD) maps can provide a wealth of information on specific marker-phenotype relationships, especially in areas of the genome where positional candidate genes with similar functions are lo...
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Article
Open AccessAn assessment of population structure in eight breeds of cattle using a whole genome SNP panel
Analyses of population structure and breed diversity have provided insight into the origin and evolution of cattle. Previously, these studies have used a low density of microsatellite markers, however, with th...
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Article
Open AccessWhole genome linkage disequilibrium maps in cattle
Bovine whole genome linkage disequilibrium maps were constructed for eight breeds of cattle. These data provide fundamental information concerning bovine genome organization which will allow the design of stud...
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Article
Open AccessHigh resolution radiation hybrid maps of bovine chromosomes 19 and 29: comparison with the bovine genome sequence assembly
High resolution radiation hybrid (RH) maps can facilitate genome sequence assembly by correctly ordering genes and genetic markers along chromosomes. The objective of the present study was to generate high res...
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Article
Open AccessA physical map of the bovine genome
Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic regions and genes affec...
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Article
Open AccessA high resolution radiation hybrid map of bovine chromosome 14 identifies scaffold rearrangement in the latest bovine assembly
Radiation hybrid (RH) maps are considered to be a tool of choice for fine map** closely linked loci, considering that the resolution of linkage maps is determined by the number of informative meiosis and rec...
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Article
Open AccessA second generation radiation hybrid map to aid the assembly of the bovine genome sequence
Several approaches can be used to determine the order of loci on chromosomes and hence develop maps of the genome. However, all map** approaches are prone to errors either arising from technical deficiencies...
