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Article
Open AccessConcurrently map** quantitative trait loci associations from multiple subspecies within hybrid populations
Many of the world’s agriculturally important plant and animal populations consist of hybrids of subspecies. Cattle in tropical and sub-tropical regions for example, originate from two subspecies, Bos taurus indic...
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Article
Open AccessInfluence of environmental factors on the detection of blood in sheep faeces using visible–near-infrared spectroscopy as a measure of Haemonchus contortus infection
Existing diagnostic methods for the parasitic gastrointestinal nematode, Haemonchus contortus, are time consuming and require specialised expertise, limiting their utility in the field. A practical, on-farm diagn...
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Article
Open AccessGenetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament
Temperament traits are of high importance across species. In humans, temperament or personality traits correlate with psychological traits and psychiatric disorders. In cattle, they impact animal welfare, prod...
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Article
Adequate supply of dietary taurine stimulates expression of molecular markers of growth and protein turnover in juvenile barramundi (Lates calcarifer)
A trial was conducted to investigate the effect of dietary taurine (Tau) supply on the plasma amino acid composition and hepatic expression of several genes in juvenile barramundi (Lates calcarifer) after feeding...
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Article
Open AccessUse of whole-genome sequence data and novel genomic selection strategies to improve selection for age at puberty in tropically-adapted beef heifers
In tropically-adapted beef heifers, application of genomic prediction for age at puberty has been limited due to low prediction accuracies. Our aim was to investigate novel methods of pre-selecting whole-genom...
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Article
Open AccessGenome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle
Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genom...
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Article
Open AccessHarnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)
Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model s...
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Article
Open AccessNon-synonymous mutations mapped to chromosome X associated with andrological and growth traits in beef cattle
Previous genome-wide association analyses identified QTL regions in the X chromosome for percentage of normal sperm and scrotal circumference in Brahman and Tropical Composite cattle. These traits are importan...
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Article
Open AccessEvidence for positive selection of taurine genes within a QTL region on chromosome X associated with testicular size in Australian Brahman cattle
Previous genome-wide association studies have identified significant regions of the X chromosome associated with reproductive traits in two Bos indicus-influenced breeds: Brahman cattle and Tropical Composites. T...
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Article
Open AccessWhole-genome resequencing of Hanwoo (Korean cattle) and insight into regions of homozygosity
Hanwoo (Korean cattle), which originated from natural crossbreeding between taurine and zebu cattle, migrated to the Korean peninsula through North China. Hanwoo were raised as draft animals until the 1970s wi...
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Article
Genome-wide copy number variation in Hanwoo, Black Angus, and Holstein cattle
Hanwoo, Korean native cattle, is indigenous to the Korean peninsula. They have been used mainly as draft animals for about 5,000 years; however, in the last 30 years, their main role has been changed to meat p...
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Article
Open AccessGenome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle
Linkage disequilibrium (LD) between genes at linked or independent loci can occur at gametic and zygotic levels known asgametic LD and zygotic LD, respectively. Gametic LD is well known for its roles in fine-s...
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Open AccessWhole genome resequencing of black Angus and Holstein cattle for SNP and CNV discovery
One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic vari...
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Article
Open AccessCharacterization of microRNA expression in bovine adipose tissues: a potential regulatory mechanism of subcutaneous adipose tissue development
MicroRNAs (miRNAs), a family of small non-coding RNA molecules, appear to regulate animal lipid metabolism and preadipocyte conversion to form lipid-assimilating adipocytes (i.e. adipogenesis). However, no miRNA ...
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Article
Open AccessA 2cM genome-wide scan of European Holstein cattle affected by classical BSE
Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion p...
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Article
Open AccessCharacterization of bovine miRNAs by sequencing and bioinformatics analysis
MicroRNAs (miRNAs) are a family of ~22 nucleotide small RNA molecules which regulate gene expression by fully or partially binding to their complementary sequences in mRNAs or promoters. A large number of miRN...
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Article
Open AccessHigh density linkage disequilibrium maps of chromosome 14 in Holstein and Angus cattle
Linkage disequilibrium (LD) maps can provide a wealth of information on specific marker-phenotype relationships, especially in areas of the genome where positional candidate genes with similar functions are lo...
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Article
Open AccessAn assessment of population structure in eight breeds of cattle using a whole genome SNP panel
Analyses of population structure and breed diversity have provided insight into the origin and evolution of cattle. Previously, these studies have used a low density of microsatellite markers, however, with th...
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Article
SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries
High-density single-nucleotide polymorphism (SNP) arrays have revolutionized the ability of genome-wide association studies to detect genomic regions harboring sequence variants that affect complex traits. Ext...
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Article
Open AccessWhole genome linkage disequilibrium maps in cattle
Bovine whole genome linkage disequilibrium maps were constructed for eight breeds of cattle. These data provide fundamental information concerning bovine genome organization which will allow the design of stud...
