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Article
Open AccessCost avoidance of pharmacist-led deprescribing using STOPPFrail for older adults in nursing homes
The Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy (STOPPFrail) criteria aim to reduce inappropriate/unnecessary medications in frail older adults, which should mini...
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Article
Open AccessEconomic cost-benefit analysis of person-centred medicines reviews by general practice pharmacists
Medicines reviews by general practice pharmacists improve patient outcomes, but little is known about the associated economic outcomes, particularly in patients at higher risk of medicines-related harm.
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Article
Open AccessDiabetes mellitus increases risk of adverse drug reactions and death in hospitalised older people: the SENATOR trial
To compare severity and type of ADRs in hospitalised, multimorbid older people with and without diabetes and to assess the impact of ADRs on mortality, rehospitalisation and length of stay.
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Article
Improving the efficiency of genetic selection in Sitka spruce using spatial and competition factors
Sitka spruce (Picea sitchensis (Bong.) Carr.), is a highly valuable commercial tree species in Ireland, UK and elsewhere in Europe but there is relatively little information available in relation to the performan...
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Article
Open AccessDormancy and Physiological Age of Seed Tubers from a Diverse Set of Potato Cultivars Grown at Different Altitudes and in Different Seasons in Kenya
The study was conducted to determine the dormancy and physiological age characteristics of diverse potato genotypes as influenced by growing altitudes and seasons for future breeding strategies and optimal pat...
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Chapter
The Role of Pharmacists in Optimising Drug Therapy
In this chapter, we aim to present and discuss the activities performed by pharmacists at individual patient level for optimising drug therapy and the role of pharmacists in training other healthcare professio...
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Article
ThinkCascades: A Tool for Identifying Clinically Important Prescribing Cascades Affecting Older People
Prescribing cascades occur when a drug is prescribed to manage side effects of another drug, typically when a side effect is misinterpreted as a new condition. A consensus list of clinically important prescrib...
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Article
Open AccessFactors influencing prescribing by critical care physicians to heart failure patients in Egypt: a cross-sectional survey
Heart failure (HF) guideline-led prescribing improves patient outcomes; however, little is known about the factors influencing guideline-led prescribing in critical care settings. This study used a cross-secti...
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Article
Open AccessAppropriateness of aspirin prescribing for primary and secondary prevention of cardiovascular disease in type 2 diabetes in different care settings
Type 2 diabetes is associated with an increased cardiovascular risk. Use of aspirin has been shown to be of benefit for secondary prevention of cardiovascular disease in patients with type 2 diabetes; benefits...
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Article
Thirst for change in a challenging environment: healthcare providers’ perceptions of safety culture in a large Irish teaching hospital
The Irish healthcare system is currently recognised as being understaffed and under-resourced due to historic underfunding and the aftermath of the 2008 global financial crisis. This descriptive study investig...
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Protocol
Genomic Prediction of Complex Traits in Forage Plants Species: Perennial Grasses Case
The majority of forage grass species are obligate outbreeders. Their breeding classically consists of an initial selection on spaced plants for highly heritable traits such as disease resistances and heading d...
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Article
Guideline-led prescribing to ambulatory heart failure patients in a cardiology outpatient service
Background Guidelines recommend heart failure (HF) patients be treated with multiple medications at doses proven to improve clinical outcomes. Objective To study guideline-led prescribing in an Irish outpatient H...
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Article
Safety culture in a major accredited Irish university teaching hospital: a mixed methods study using the safety attitudes questionnaire
The measurement of safety culture, the way in which members of an organisation think about and prioritise safety, in a hospital can provide valuable insight and inform quality improvement strategies.
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Article
Open AccessMeasurement properties of EQ-5D-3L and EQ-5D-5L in recording self-reported health status in older patients with substantial multimorbidity and polypharmacy
The EQ-5D-3L and EQ-5D-5L are two generic health-related quality of life measures, which may be used in clinical and health economic research. They measure impairment in 5 aspects of health: mobility, self-car...
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Article
Factors Affecting Prescriber Implementation of Computer-Generated Medication Recommendations in the SENATOR Trial: A Qualitative Study
The SENATOR trial intervention included the provision of computer-generated medication recommendations to physician prescribers caring for hospitalised older adults (≥ 65 years), with the aim of reducing in-ho...
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Article
Open AccessIntervention protocol: OPtimising thERapy to prevent avoidable hospital Admission in the Multi-morbid elderly (OPERAM): a structured medication review with support of a computerised decision support system
Several approaches to medication optimisation by identifying drug-related problems in older people have been described. Although some interventions have shown reductions in drug-related problems (DRPs), eviden...
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Article
Rapid Development of KASP Markers for Disease Resistance Genes Using Pooled Whole-Genome Resequencing
Marker-assisted selection (MAS) is becoming increasingly common in commercial potato breeding programmes and can provide information to breeders on potential resistance to diseases and pests early in the breed...
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Article
Psychometric Properties of the Emotion Reactivity Scale in Community Screening Assessments
Among individuals experiencing internalizing psychopathology, high levels of emotion reactivity—the degree to which they experience emotions strongly or intensely, over extended periods of time, and as elicite...
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Article
Pharmacist-led academic detailing intervention in primary care: a mixed methods feasibility study
Background Academic detailing is a form of continuing medical education in which a trained health professional such as a physician or pharmacist visits prescribers in their practice to provide evidence-based info...
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Article
Open AccessPooled DNA sequencing to identify SNPs associated with a major QTL for bacterial wilt resistance in Italian ryegrass (Lolium multiflorum Lam.)
SNPs and candidate genes associated with bacterial wilt resistance in Italian ryegrass were identified by sequencing the parental plants and pooled F1 progeny of a segregating population.
