60 Result(s)
within
Stephen Brown
English
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Article
Open AccessCorrection: Undernutrition in young children with congenital heart disease undergoing cardiac surgery in a low‑income environment
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Chapter
Jazzin’ Jim, Talkin’ Tut: A Colonialist Confesses
One hundred years ago, two landmark events occurred in the cultural sphere. Both have been deemed the ‘birth’ of postcolonialism. James Joyce published Ulysses, an infamous novel about Ireland, written in exile. ...
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Article
Factors influencing mercury exposure in Arctic-breeding shorebirds
Mercury (Hg) pollution remains a concern to Arctic ecosystems, due to long-range transport from southern industrial regions and melting permafrost and glaciers. The objective of this study was to identify intr...
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Article
Open AccessImpairment in sleep health in young adults with chronic pain: a modifiable risk factor
Impairments in sleep health are associated with the development or worsening of chronic pain. Further, chronic pain can cause sleep health disruption by impacting sleep onset, sleep maintenance, sleep quality,...
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Article
Open AccessBoosting neuregulin 1 type-III expression hastens SMA motor axon maturation
Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation. In the early onset motor neuron disease spinal muscular atro...
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Chapter
Measurement of Glomerular Filtration Rate (GFR)
Glomerular Filtration Rate (GFR) is the volume of plasma filtered by the glomeruli in mls/min. It can be measured as the clearance of any substance that is filtered but not actively secreted or reabsorbed by t...
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Article
Open AccessImproved constraints on effective top quark interactions using edge convolution networks
We explore the potential of Graph Neural Networks (GNNs) to improve the performance of high-dimensional effective field theory parameter fits to collider data beyond traditional rectangular cut-based different...
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Chapter and Conference Paper
Small-Scale Rapid Alloy Prototy** of Extra-Low Carbon Steel to Investigate the Effects of Cu and Cr Residuals
A (RAP) route is presented for accelerated lab-scale development of across many applications in which alloys can be tailored with individual or combined elements to a compositional precision down to 0.1%. ...
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Article
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
Heterobifunctional chimeric degraders are a class of ligands that recruit target proteins to E3 ubiquitin ligases to drive compound-dependent protein degradation. Advancing from initial chemical tools, protein...
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Chapter
Going Viral: Development Assistance Under the Trudeau Minority Government
This chapter traces the evolution of Canadian aid in the first year of the Trudeau minority government, beginning with an examination of the electoral context and its immediate aftermath. It then analyzes the ...
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Article
Open AccessThe Rise and Fall of the Aid Effectiveness Norm
This article analyzes the rise and fall of the aid effectiveness norm, using the lens of Finnemore and Sikkink’s norm ‘life cycle’. I argue that, although donors and recipients endorsed the founding principles...
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Article
Open AccessThe Use of Computer Simulation Modeling to Estimate Complications in Patients with Type 2 Diabetes Mellitus: Comparative Validation of the Cornerstone Diabetes Simulation Model
The objective of this study was to assess the validity of the Cornerstone Diabetes Simulation (CDS), a Microsoft Excel®-based patient-level simulation for type 2 diabetes mellitus based on risk equations from the...
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Chapter
Reproductive Genetics for the Clinician
A practicing reproductive endocrinologist encounters patients with genetic issues and questions on a daily basis. This may include women with age-related risk of aneuploidy, couples that are carriers of Mendel...
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Article
Open AccessComprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks
Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...
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Chapter
Intellectual Disability and Epilepsy
Epilepsy in people with intellectual disability is more than the sum of the two conditions. Diagnosis is challenging in the face of cognitive and communication difficulties and in some instances the need to re...
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Article
Open AccessKinetic modeling of tumor regression incorporating the concept of cancer stem-like cells for patients with locally advanced lung cancer
Personalized medicine for patients receiving radiation therapy remains an elusive goal due, in part, to the limits in our understanding of the underlying mechanisms governing tumor response to radiation. The p...
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Article
Open AccessThe Hiperwall tiled-display wall system for Big-Data research
In the era of Big Data, with the increasing use of large-scale data-driven applications, visualization of very large high-resolution images and extracting useful information (searching for specific targets or ...
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Article
Open AccessACTA2 mutation and postpartum hemorrhage: a case report
ACTA2 encodes smooth muscle specific α-actin, a critical component or the contractile complex of vascular smooth muscle. Mutations in ACTA2 are the most common genetic cause of thoraci...
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Article
Open AccessRe-examining the ECB’s two-pillar monetary policy strategy: Are there any deviations during and the pre-financial crisis periods?
This paper addresses the extent to which the ECB rate setting responded to inflation and monetary growth in the run up to, and during, the financial crisis of the late 2000s. The analysis covers the period bet...
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Article
Breast Durometer (Mammometer): A Novel Device for Measuring Soft-Tissue Firmness and Its Application in Cosmetic Breast Surgery
The measurement of soft-tissue firmness has many potential applications in medical practice. This study reports a user-friendly, novel device that is capable of measuring changes in soft-tissue firmness in a r...
