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Article
Open AccessGenetic diversity and connectivity of moose (Alces americanus americanus) in eastern North America
Genetic diversity is critical to a population’s ability to overcome gradual environment change. Large-bodied wildlife existing in regions with relatively high human population density are vulnerable to isolati...
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Article
Open AccessA 2cM genome-wide scan of European Holstein cattle affected by classical BSE
Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion p...
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Article
Open AccessHigh resolution radiation hybrid maps of bovine chromosomes 19 and 29: comparison with the bovine genome sequence assembly
High resolution radiation hybrid (RH) maps can facilitate genome sequence assembly by correctly ordering genes and genetic markers along chromosomes. The objective of the present study was to generate high res...
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Article
Open AccessA physical map of the bovine genome
Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic regions and genes affec...
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Article
Open AccessA second generation radiation hybrid map to aid the assembly of the bovine genome sequence
Several approaches can be used to determine the order of loci on chromosomes and hence develop maps of the genome. However, all map** approaches are prone to errors either arising from technical deficiencies...