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Use of teplizumab in children and adolescents at risk of type 1 diabetes: perspectives of parents and caregivers from an Italian Pediatric Diabetes Center
In view of the imminent introduction of a novel category of disease-modifying treatments for type 1 diabetes (T1D) in European countries, it becomes imperative to understand the existing awareness and viewpoin...
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Article
Open AccessMaintaining a gluten-free diet is associated with quality of life in youths with type 1 diabetes and celiac disease
Conflicting findings have been reported on whether in youths, the double diagnosis of type 1 diabetes (T1D) and celiac disease (CD) substantially impacts quality of life QoL, compared to subjects with T1D only.
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Article
Open AccessSafety, Metabolic and Psychological Outcomes of Medtronic MiniMed 780G™ in Children, Adolescents and Young Adults: A Systematic Review
The MiniMed™ 780G is a second-generation automated insulin delivery system that implements a modified proportional–integral–derivative algorithm with some features of an MD-Logic artificial pancreas algorithm....
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Open AccessPrevalence and clinical features of severe diabetic ketoacidosis treated in pediatric intensive care unit: a 5-year monocentric experience
Diabetic ketoacidosis (DKA) is one of the most alarming concerns in the management of type 1 diabetes (T1D) in pediatric age. Prevalence of DKA at the onset of diabetes ranges from 30 to 40%. In selected cases...
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Article
Italian translation and validation of the CGM satisfaction scale questionnaire
Patient-reported outcomes (PROs) are increasingly important for assessing patient satisfaction with diabetes technologies. PROs must be assessed with validated questionnaires in clinical practice and research ...
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Article
Open AccessIncreasing trend of type 1 diabetes incidence in the pediatric population of the Calabria region in 2019–2021
Although type 1 diabetes (T1D) represents one of the most common chronic diseases in pediatric age, few studies on the epidemiology of T1D exist globally and the exact prevalence and incidence rates of the dis...
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Article
Open AccessLong term treatment with omalizumab in adolescent with refractory solar urticaria
Solar urticaria represents an uncomfortable form of chronic inducible urticaria. First and second-line treatments are ineffective in some patients, leading to an impairment in their quality of life. Omalizumab...
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Article
Open AccessClinical and genetic features of maturity-onset diabetes of the young in pediatric patients: a 12-year monocentric experience
A retrospective observational study was conducted to assess the prevalence of maturity onset diabetes of the young (MODY) in a large paediatric population of Southern Italy newly diagnosed with diabetes. Clini...
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Article
Open AccessImplications of SARS-COV-2 infection in the diagnosis and management of the pediatric gastrointestinal disease
Gastrointestinal diseases such as celiac disease, functional gastrointestinal disorders (FGIDs), inflammatory bowel disease (IBDs) and acute or chronic diarrhea are quite frequent in the pediatric population. ...
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Article
Open AccessQuarantine due to the COVID-19 pandemic from the perspective of adolescents: the crucial role of technology
The year 2020 will be remembered as the “year of the COVID-19 pandemic”. The world population had to familiarize themselves with words as swabs, personal protective equipment, pandemic. To curb the wave of the...
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Article
Open AccessScurvy may occur even in children with no underlying risk factors: a case report
Since ancient times, scurvy has been considered one of the most fearsome nutritional deficiency diseases. In modern developed countries, this condition has become very rare and is only occasionally encountered...
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Article
Open AccessMaturity Onset Diabetes of the Young is Not Necessarily Associated with Autosomal Inheritance: Case Description of a De Novo HFN1A Mutation
Maturity onset diabetes of the young (MODY) accounts for up to 4% of all cases of diabetes in pediatric patients. MODY is usually characterized by autosomal dominant inheritance, impaired insulin secretion, an...
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Article
Open AccessHepatomegaly and type 1 diabetes: a clinical case of Mauriac’s syndrome
Hepatic glycogenosis is characterized by excessive glycogen accumulation in hepatocytes and represents a complication of poor controlled type 1 diabetes. It can be caused by excessive insulin doses or recurren...
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Open AccessPrehypertension in adolescents with cardiovascular risk: a comparison between type 1 diabetic patients and overweight subjects
Adolescents with type 1 diabetes and obesity present higher cardiovascular risk and ambulatory blood pressure measurements (ABPM) has been shown to predict vascular events, especially by identifying the nondip...
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Open AccessRecurrent hypoglycaemia in type-1 diabetes mellitus may unravel the association with Addison’s disease: a case report
Primary adrenocortical insufficiency or Addison’s disease is caused by a progressive destruction of the adrenal cortex, resulting into a reduction of glucocorticoids, mineralocorticoids, and androgens. Autoimm...