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Article
Open AccessDoes age really matter? Radiotherapy in elderly patients with glioblastoma, the Munich experience
Glioblastoma is usually diagnosed around the age of 60–70 years. Patients older than 65 years are frequently described as “elderly”. Several trials with monotherapy have established treatment regimens that off...
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Article
Open AccessSafe Brain Tumor Resection Does not Depend on Surgery Alone - Role of Hemodynamics
Aim of this study was to determine if perioperative hemodynamics have an impact on perioperative infarct volume and patients’ prognosis. 201 cases with surgery for a newly diagnosed or recurrent glioblastoma w...
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Article
Open AccessImpact of ischemic preconditioning on surgical treatment of brain tumors: a single-center, randomized, double-blind, controlled trial
Postoperative ischemia is a frequent phenomenon in patients with brain tumors and is associated with postoperative neurological deficits and impaired overall survival. Particularly in the field of cardiac and ...
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Article
Open AccessDiffusion tensor image features predict IDH genotype in newly diagnosed WHO grade II/III gliomas
We hypothesized that machine learning analysis based on texture information from the preoperative MRI can predict IDH mutational status in newly diagnosed WHO grade II and III gliomas. This retrospective study in...
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Article
Open AccessFactors influencing neurocognitive function in patients with neuroepithelial tumors
Though cognitive function is proven to be an independent predictor of survival in patients with intrinsic brain tumors, cognitive functions are still rarely considered. Aim of this study was to assess neurocog...
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Article
Open AccessPublisher Correction: Factors influencing neurocognitive function in patients with neuroepithelial tumors
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessRetrospective Analysis of Radiological Recurrence Patterns in Glioblastoma, Their Prognostic Value And Association to Postoperative Infarct Volume
Recent studies suggested that postoperative hypoxia might trigger invasive tumor growth, resulting in diffuse/multifocal recurrence patterns. Aim of this study was to analyze distinct recurrence patterns and t...
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Article
Open AccessPersonality Traits in Patients with Neuroepithelial Tumors – A Prospective Study
Aim of this study was to analyze personality traits in patients with neuroepithelial brain tumors. Personality alteration is a common feature in brain tumor patients, but not much is known about associations b...
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Article
Open AccessRisk factors for neurocognitive impairment in patients with benign intracranial lesions
This study was designed to assess risk factors for neurocognitive impairment in patients with benign intracranial lesions including tumors and vascular lesions. 74 patients (29 m, 51 f, mean age 54.4 years) wi...
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Article
Open AccessPostoperative cognitive functions in patients with benign intracranial lesions
The aim of this study was to assess pre- and postoperative cognitive functions in patients who underwent surgery for benign intracranial lesions. In total, 58 patients (21 men, 37 women, mean age 51.6 years [r...
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Article
Open AccessVisual acuity and its postoperative outcome after transsphenoidal adenoma resection
Transsphenoidal surgery (TSS) represents the gold standard of pituitary adenoma resection, providing a safe and minimal invasive treatment for patients suffering from symptoms of mass effect. The aim of this s...
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Article
Open AccessPrognostic value of tumour volume in patients with a poor Karnofsky performance status scale – a bicentric retrospective study
Median overall survival (OS) after diagnosis of glioblastoma (GBM) remains 15 months amongst patients receiving aggressive surgical resection, chemotherapy and irradiation. Treatment of patients with a poor pr...
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Article
Open AccessAge-adjusted Charlson comorbidity index in recurrent glioblastoma: a new prognostic factor?
For recurrent glioblastoma (GB) patients, several therapy options have been established over the last years such as more aggressive surgery, re-irradiation or chemotherapy. Age and the Karnofsky Performance St...
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Article
Open AccessTranssphenoidal pituitary adenoma resection: do early post-operative cortisol levels predict permanent long-term hypocortisolism?
Transsphenoidal surgery provides a minimal invasive treatment for pituitary adenoma. Our aim is to evaluate the endocrinological outcomes after adenoma resection focusing on the corticotroph function, and to i...
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Article
Open AccessComparison and Trends of Endovascular, Surgical and Hybrid Revascularizations and the Influence of Comorbidity in 1 Million Hospitalizations Due to Peripheral Artery Disease in Germany Between 2009 and 2018
To analyze trends and differences of endovascular, surgical and hybrid revascularization approaches and the impact of comorbidity on characteristics, costs, and outcome of in-patients with peripheral artery di...
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Article
Open AccessAssessment of epicardial adipose tissue on virtual non-contrast images derived from photon-counting detector coronary CTA datasets
To assess epicardial adipose tissue (EAT) volume and attenuation of different virtual non-contrast (VNC) reconstructions derived from coronary CTA (CCTA) datasets of a photon-counting detector (PCD) CT-system ...
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Article
Open AccessIdentification of radiomic biomarkers in a set of four skeletal muscle groups on Dixon MRI of the NAKO MR study
In this work, we propose a processing pipeline for the extraction and identification of meaningful radiomics biomarkers in skeletal muscle tissue as displayed using Dixon-weighted MRI. Diverse and robust radio...
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Article
Open AccessGerman nation-wide in-patient treatment of abdominal aortic aneurysm—trends between 2005 and 2019 and impact of the SARS-CoV-2 pandemic
Aim of this study was to analyze hospitalizations due to ruptured and non-ruptured abdominal aortic aneurysms (rAAA, nrAAA) in Germany between 2005 and 2021 to determine long-term trends in treatment and the i...
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Article
Open AccessTreatment of acute mesenteric ischemia between 2010 and 2020 – a German nation-wide study
Aim of this study was to analyze long-term trends of hospitalizations, treatment regimen and in-hospital mortality of in-patients with acute mesenteric ischemia (AMI) over the past decade and effects of the SA...
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Article
Open AccessOptimal conspicuity of pancreatic ductal adenocarcinoma in virtual monochromatic imaging reconstructions on a photon-counting detector CT: comparison to conventional MDCT
To analyze the conspicuity of pancreatic ductal adenocarcinoma (PDAC) in virtual monoenergetic images (VMI) on a novel photon-counting detector CT (PCD-CT) in comparison to energy-integrating CT (EID-CT).
