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Article
Open AccessSchwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
Facial nerve schwannomas account for about 0.8% of all petrous mass lesions. Schwannomas of the greater superficial petrosal nerve (GSPN) are a rare subtype with few case-reports up to date.
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Article
Open AccessAge-adjusted Charlson comorbidity index in recurrent glioblastoma: a new prognostic factor?
For recurrent glioblastoma (GB) patients, several therapy options have been established over the last years such as more aggressive surgery, re-irradiation or chemotherapy. Age and the Karnofsky Performance St...
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Article
Open AccessPrognostic value of tumour volume in patients with a poor Karnofsky performance status scale – a bicentric retrospective study
Median overall survival (OS) after diagnosis of glioblastoma (GBM) remains 15 months amongst patients receiving aggressive surgical resection, chemotherapy and irradiation. Treatment of patients with a poor pr...
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Article
Open AccessVisualizing cellularity and angiogenesis in newly-diagnosed glioblastoma with diffusion and perfusion MRI and FET-PET imaging
Combining imaging modalities has become an essential tool for assessment of tumor biology in glioblastoma (GBM) patients. Aim of this study is to understand how tumor cellularity and neovascularization are ref...
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Article
Open AccessThe interhemispheric fissure—surgical outcome of interhemispheric approaches
Exposure of the anterior skull base is challenging due to strategic structures. The interhemispheric approach (IHA) has turned out to be a feasible technique. We report our experience with IHAs in patients wit...
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Article
Minimally invasive posterior pedicle screw fixation versus open instrumentation in patients with thoracolumbar spondylodiscitis
Due to the aging society, the incidence of pyogenic spondylodiscitis is still rising. Although surgical treatment for spondylodiscitis in general is increasingly accepted, an optimal surgical strategy for trea...
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Article
Open AccessPostoperative cognitive functions in patients with benign intracranial lesions
The aim of this study was to assess pre- and postoperative cognitive functions in patients who underwent surgery for benign intracranial lesions. In total, 58 patients (21 men, 37 women, mean age 51.6 years [r...
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Article
Open AccessThe transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
A variety of sinonasal tumours, meningiomas or other lesions of the anterior skull base involve the paranasal sinuses and the periorbital area. The transbasal approach (TBA) has turned out to be a feasible tec...
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Article
Open AccessIntraventricular neuroepithelial tumors: surgical outcome, technical considerations and review of literature
Intraventricular neuroepithelial tumors (IVT) are rare lesions and comprise different pathological entities such as ependymomas, subependymomas and central neurocytomas. The treatment of choice is neurosurgica...
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Article
Perioperative neurocognitive functions in patients with neuroepithelial intracranial tumors
This study aimed to assess perioperative neurocognitive functions in patients with surgery for intracranial neuroepithelial tumors.
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Article
Open AccessRisk factors for neurocognitive impairment in patients with benign intracranial lesions
This study was designed to assess risk factors for neurocognitive impairment in patients with benign intracranial lesions including tumors and vascular lesions. 74 patients (29 m, 51 f, mean age 54.4 years) wi...
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Article
Role of postoperative tumor volume in patients with MGMT-unmethylated glioblastoma
The aim of this study is to investigate the association between postoperative tumor volume and overall survival (OS) of O6-methylguanine DNA methyltransferase (MGMT)-unmethylated glioblastoma patients.
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Article
Open AccessRetrospective Analysis of Radiological Recurrence Patterns in Glioblastoma, Their Prognostic Value And Association to Postoperative Infarct Volume
Recent studies suggested that postoperative hypoxia might trigger invasive tumor growth, resulting in diffuse/multifocal recurrence patterns. Aim of this study was to analyze distinct recurrence patterns and t...
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Article
Open AccessImpact of ischemic preconditioning on surgical treatment of brain tumors: a single-center, randomized, double-blind, controlled trial
Postoperative ischemia is a frequent phenomenon in patients with brain tumors and is associated with postoperative neurological deficits and impaired overall survival. Particularly in the field of cardiac and ...
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Article
Open AccessSafe Brain Tumor Resection Does not Depend on Surgery Alone - Role of Hemodynamics
Aim of this study was to determine if perioperative hemodynamics have an impact on perioperative infarct volume and patients’ prognosis. 201 cases with surgery for a newly diagnosed or recurrent glioblastoma w...
