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Article
Open AccessNeural responses to acute stress predict chronic stress perception in daily life over 13 months
The importance of amygdala, hippocampus, and medial prefrontal cortex (mPFC) for the integration of neural, endocrine, and affective stress processing was shown in healthy participants and patients with stress...
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Article
Exploring the differential contribution of boldness, meanness, and disinhibition to explain externalising and internalising behaviours across genders
Psychopathic personality traits are positively associated with externalising behaviours, and negatively associated with internalising behaviours. However, the contribution of different facets of psychopathy (b...
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Article
Open AccessDissociation of behavioral and neural responses to provocation during reactive aggression in healthy adults with high versus low externalization
The externalizing spectrum describes a range of heterogeneous personality traits and behavioral patterns, primarily characterized by antisocial behavior, disinhibition, and substance (mis)use. In psychopatholo...
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Article
Open AccessHair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes
Hair cortisol concentration (HCC) is a promising measure of long-term hypothalamus-pituitary-adrenal (HPA) axis activity. Previous research has suggested an association between HCC and psychological variables,...
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Article
Neural Correlates of the Cortisol Awakening Response in Humans
The cortisol rise after awakening (cortisol awakening response, CAR) is a core biomarker of hypothalamic-pituitary-adrenal (HPA) axis regulation related to psychosocial stress and stress-related psychiatric di...
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Article
Perceived Stress has Genetic Influences Distinct from Neuroticism and Depression
The present study investigated whether the genetic determinants of neuroticism and depressive symptoms differ from those underlying perceived psychological stress. Multivariate structural equation models, whic...
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Article
Risikogene der Schizophrenie und ihre neuralen Effekte
Die Schizophrenie weist eine Erblichkeit von etwa 80 Prozent auf. Daher sind die Identifikation der zugrunde liegenden Gene und die Aufdeckung der neurogenetischen Mechanismen von größter Bedeutung für das Ver...
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Article
City living and urban upbringing affect neural social stress processing in humans
By 2050, two-thirds of the world's population will be living in cities. Although city living has many advantages, rapidly increasing urbanization has major health implications — schizophrenia is more common in...
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Article
Transcriptional control of the human glucocorticoid receptor: identification and analysis of alternative promoter regions
Glucocorticoid receptor levels are thought to be controlled by multiple alternative first exons. Seven of these exons are located in an upstream CpG island. In this study, we investigated the promoter activity...
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Article
Computer-based training for the treatment of partial blindness
Partial blindness after brain injury has been considered non-treatable. To evaluate whether patients with visual-field defects can profit from computer-based visual restitution training (VRT), tw...
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Cortisol and Behavior: The “Trier Mental Challenge Test” (TMCT) — First Evaluation of a New Psychological Stress Test
The activity of the hypothalamus-pituitary-adrenal (HPA) axis is regulated by a variety of stimuli in mammals. Besides the well established circadian rhythm of HPA activity (Weitzman et al., 1971) pharmacologi...
