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  1. Article

    Open Access

    Association of rural living with COPD-related hospitalizations and deaths in US veterans

    It is unclear whether the high burden of COPD in rural areas is related to worse outcomes in patients with COPD or is because the prevalence of COPD is higher in rural areas. We assessed the association of rur...

    Spyridon Fortis, Yubo Gao, Arianne K. Baldomero in Scientific Reports (2023)

  2. Article

    Open Access

    Low FVC/TLC in Preserved Ratio Impaired Spirometry (PRISm) is associated with features of and progression to obstructive lung disease

    One quarter of individuals with Preserved Ratio Impaired Spirometry (PRISm) will develop airflow obstruction, but there are no established methods to identify these individuals. We examined the utility of FVC/...

    Spyridon Fortis, Alejandro Comellas, Victor Kim, Richard Casaburi in Scientific Reports (2020)

  3. No Access

    Chapter

    Structure and Design of the Tele-ICU

    In this chapter, we describe how to build a centralized tele-ICU program. We provide information regarding the various tele-ICU operational models, the roles of the tele-ICU staff, and the technological requir...

    Spyridon Fortis, Matthew R. Goede in Telemedicine in the ICU (2019)

  4. Article

    Open Access

    Perseverant, non-indicated treatment of obese patients for obstructive lung disease

    Bronchodilators are a mainstay of treatment for patients with airflow obstruction. We hypothesized that patients with obesity and no objective documentation of airflow obstruction are inappropriately treated w...

    Spyridon Fortis, Joseph Kittah, Manuel De Aguirre, Maria Plataki in BMC Pulmonary Medicine (2013)

  5. Article

    Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury

    Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter through activation of GABA receptors. Volatile anesthetics activate type-A (GABAA) receptors resulting in inhibition of synaptic transmissio...

    Spyridon Fortis, Peter M. Spieth, Wei-Yang Lu, Matteo Parotto in Intensive Care Medicine (2012)