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Article
Open AccessThe effect of air pollution on the transcriptomics of the immune response to respiratory infection
Combustion related particulate matter air pollution (PM) is associated with an increased risk of respiratory infections in adults. The exact mechanism underlying this association has not been determined. We hy...
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Article
Open AccessAuthor Correction: Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessTranscriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
Candida albicans is a diploid fungus and a predominant opportunistic human pathogen. Notably, C. albicans employs reversible chromosomal aneuploidies as a means of survival in adverse environments. We previously ...
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Article
Open AccessTranscriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness
Lower respiratory tract infection (LRTI) commonly causes hospitalization in adults. Because bacterial diagnostic tests are not accurate, antibiotics are frequently prescribed. Peripheral blood gene expression ...
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Article
Open AccessMicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells
While all forms of tobacco exposure have negative health effects, the significance of exposure to electronic cigarettes (eCig) is not fully understood. Here, we studied the global effects of eCig on the micro ...
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Article
Open AccessThe Healthy Infant Nasal Transcriptome: A Benchmark Study
Responses by resident cells are likely to play a key role in determining the severity of respiratory disease. However, sampling of the airways poses a significant challenge, particularly in infants and childre...