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  1. Article

    Open Access

    3D cell sheet structure augments mesenchymal stem cell cytokine production

    Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during tissue regeneration. An increasing body of evidence suggests that this paracrine function is enhanced by MSC cultivation i...

    Sophia Bou-Ghannam, Kyungsook Kim, David W. Grainger, Teruo Okano in Scientific Reports (2021)

  2. Article

    Open Access

    Human mesenchymal stem cell sheets in xeno-free media for possible allogenic applications

    Cell-based therapies are increasingly focused on allogeneic stem cell sources because of several advantages in eliminating donor variability (e.g., aging and disease pathophysiology) affecting stem cell qualit...

    Kyungsook Kim, Sophia Bou-Ghannam, Hallie Thorp, David W. Grainger in Scientific Reports (2019)